ArticleKorean journal of radiology
Degradable gelatin microspheres as an embolic agent: an experimental study in a rabbit renal model.
Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 42 citations in OpenAlex.
- Bioresorbable Gelatin Microspheres for Temporary Transarterial Embolization: Feasibility Study in Porcine Kidney Model.Cardiovascular and interventional radiology · 2025Article
- Article
- Transarterial Embolization and Percutaneous Ablation of Primary and Metastatic Soft Tissue Tumors.Life (Basel, Switzerland) · 2023Review
- Characteristics and efficacy of fish-derived gelatin microparticles as an embolic agent in a rabbit renal model: regulation of the degradation period by molecular weight.Diagnostic and interventional radiology (Ankara, Turkey) · 2022Article
- Transarterial Radioembolization Agents: a Review of the Radionuclide Agents and the Carriers.Nuclear medicine and molecular imaging · 2021Review
- Fat tissue as an embolic material changes the embolization time in a size-dependent manner: a basic investigation using rabbits.Japanese journal of radiology · 2021Article
- Article
- Embolic effects of Bletilla striata microspheres in renal artery and transplanted VX2 liver tumor model in rabbits.Chinese journal of integrative medicine · 2019Article
- Advances in Degradable Embolic Microspheres: A State of the Art Review.Journal of functional biomaterials · 2018Review
- Calibrated Bioresorbable Microspheres as an Embolic Agent: An Experimental Study in a Rabbit Renal Model.Journal of vascular and interventional radiology : JVIR · 2015Article
- Anti-tumour effects of transcatheter arterial embolisation administered in combination with thalidomide in a rabbit VX2 liver tumour model.The British journal of radiology · 2011Article
- Direct in vivo injection of 131I-GMS and its distribution and excretion in rabbit.World journal of gastroenterology · 2010Article
- A combination of cisplatin-eluting gelatin microspheres and flavopiridol enhances anti-tumour effects in a rabbit VX2 liver tumour model.The British journal of radiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the basic characteristics of degradable gelatin microspheres (GMSs), including their embolic behavior and degradation periods when they are used as embolic materials in the renal arteries of rabbit models. MATERIALS AND
methodsBased on the GMS particle size, 24 kidneys were divided into 3 groups of eight kidneys, and each group was embolized with a different GMS particle size (group 1: 35-100 microm, group 2: 100-200 microm, and group 3: 200-300 microm). From each group, two rabbits were sacrificed immediately after embolization (day 0), and a pair of rabbits from each group underwent an angiogram and were sacrificed on days 3, 7, and 14, respectively, after embolization. The level of arterial occlusion, the pathological changes in the renal parenchyma, and the degradation of the GMSs were evaluated angiographically and histologically.
resultsA follow-up angiogram on days 0, 3, 7, and 14 revealed the presence of wedge-shaped poorly-enhanced areas in the parenchymal phase as seen in all groups. The size of these areas tended to increase with the particle diameter, and persisted up to day 14. On days 3, 7, and 14, parenchymal infarctions were observed histologically in all cases, and this observation corresponded with the parenchyma being supplied by the embolized arteries. GMSs of group 1 mainly reached the interlobular arteries, while those of group 3 mainly reached the interlobar arteries. In all but two cases, the GMSs were identified histologically even on day 14, and sequential degradation was histologically identified in all GMS groups.
conclusionGMSs can be used as degradable embolic materials which can control the level of embolization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.