ArticleBMC infectious diseases2007
Molecular epidemiology of Hepatitis B virus genotypes in Pakistan.
Article in BMC infectious diseases, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Hepatitis B virus in Pakistan: a systematic review of prevalence, risk factors, awareness status and genotypes.Virology journal · 2011Pooled it
- Viruses that cross borders: factors responsible for global dissemination of viral infections.Intervirology · 2011Pooled it
- Distribution of hepatitis B virus genotypes and demography in the general population of Karachi, Sindh.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Prevalence of hepatitis B virus surface antigen, associated risk factors, and liver enzyme abnormalities among individuals with diabetes in Aksum town public hospitals, Tigray, northern Ethiopia.The Pan African medical journal · 2024Article
- A Recent Prevalence of Hepatitis B Virus (HBV) Genotypes and Subtypes in Asia: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Molecular and genetic characterization of hepatitis B virus among multitransfused thalassaemia patients in Islamabad, Pakistan.Journal of family medicine and primary care · 2021Article
- Case Report: Application of hepatitis B virus (HBV) deep sequencing to distinguish between acute and chronic infection.Wellcome open research · 2020Article
- In Silico Analysis of Hepatitis B Virus Genotype D Subgenotype D1 Circulating in Pakistan, China, and India.Evolutionary bioinformatics online · 2019Article
- Serum lipid profile as a marker of liver impairment in hepatitis B Cirrhosis patients.Lipids in health and disease · 2017Article
- A Diagnostic Laboratory-Based Study on Frequency and Distribution of Viral Hepatitis B and C Among Sudanese.The open virology journal · 2017Article
- Article
- Article
- Distribution and clinical significance of hepatitis B virus genotypes in Pakistan.BMC gastroenterology · 2016Article
- Hepatitis B virus genotypes among chronic hepatitis B patients reporting at Korle-Bu teaching hospital, Accra, Ghana.The Pan African medical journal · 2016Article
- Prevalence of hepatitis B and C and relationship to liver damage in HIV infected patients attending Joint Clinical Research Centre Clinic (JCRC), Kampala, Uganda.African health sciences · 2015Article
- Genotypes and viral variants in chronic hepatitis B: A review of epidemiology and clinical relevance.World journal of hepatology · 2015Review
- Hepatitis B Virus Genotypes Distribution with HBsAg Positive in the North of Iran (Mazandaran) During 2011-2014.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2014Article
- Prevalence and genotypes of hepatitis B virus infection in patients underwent coronary angiography and coronary artery bypass grafting in mazandaran heart center, sari, iran.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2014Article
- A Hospital-based Retrospective Study on Frequency and Distribution of Viral Hepatitis.Journal of global infectious diseases · 2014Article
- Hepatitis B virus DNA level Among the Seropositive Afghan Immigrants, Southern Iran.Jundishapur journal of microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEight genotypes of Hepatitis B virus designated A-H, have been known but in Pakistan, no such data is available on the prevalent HBV genotypes. Therefore, the subject study was conducted to determine HBV genotypes in the indigenous Pakistani population.
methodsA total of 690 individuals were enrolled for HBV screening with EIA and nested PCR. Positive samples were further analyzed to determine HBV genotypes (A-F) by multiplex-PCR using type specific primers.
results110 (15.94%) individuals were positive for HBV, including 64% males and 36% females. Out of these, 66 samples (65.34%) were classified into genotype D, 27 (26.73%) were of genotype B while 5(4.95%) had genotype A. In 3 (2.98%) samples, multiple genotypes were detected (genotype A+B; 2(1.99%) and genotypes B+D; 1(0.99%). Nine (8.18%) samples remained untyable.
conclusionIn Asia, genotypes B and C are the most prevalent but our study reveals that genotype D is predominant and HBV infection constitutes a significant health problem in Pakistan.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.