Evidence map›Paper›PMID 17922175›Full record

ArticleJournal of fluorescence2007

Plasmonic enhancement of single-molecule fluorescence near a silver nanoparticle.

Yi Fu, Jian Zhang, Joseph R Lakowicz

Open access · greenAbstract read
In one paragraph

Article in Journal of fluorescence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 88 citations in OpenAlex.

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  10. Harnessing Leaky Modes for Fluorescence Enhancement in Gold-Tipped Silicon Nanowires.The journal of physical chemistry. C, Nanomaterials and interfaces · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yi FuCenter for Fluorescence Spectroscopy, University of Maryland School of Medicine, 725 W. Lombard Street, Baltimore, MD 21201, USA.
Jian Zhang
Joseph R Lakowicz
University of Maryland, Baltimore · US

Funding

Metallic Surfaces and Particles in DNA AnalysisR01HG002655 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI LAKOWICZ, JOSEPH R. · 2003 to 2012
$2.8M
NHGRI NIH HHS HG 02655NHGRI NIH HHS R01 HG002655
6 · The paper itself

Abstract

In this short paper, we reported the enhanced fluorescence from a single fluorophore bound to a 50nm silver nanoparticle. We found that on average the Cy5 molecules bound to metal nanoparticles are approximately 15-fold brighter than that of free dyes, and that single molecule lifetimes are shorter as compared to free fluorophores. The increased emission rate is primarily the result of local plasmon enhancement. These results demonstrate that the use of fluorophore-metal interactions can increase the brightness and photostability of fluorophores for single molecule detection.

Indexed as

Metal NanoparticlesSilverBase SequenceCarbocyaninesFluorescent DyesMicroscopy, ConfocalMicroscopy, FluorescenceOligodeoxyribonucleotidesPhotobleachingPhotochemistrySpectrometry, FluorescenceSurface Plasmon ResonanceCarbocyaninescyanine dye 5Fluorescent DyesOligodeoxyribonucleotidesSilver

Identifiers

PMID17922175
PMCPMC2763915
OpenAlexW2127622793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.