ArticleApplied and environmental microbiology2007
Detection of bacteriophage-infected cells of Lactococcus lactis by using flow cytometry.
Article in Applied and environmental microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reassessment of Historical Clinical Trials Supports the Effectiveness of Phage Therapy.Clinical microbiology reviews · 2022Pooled it
- Development and validation of a LAMP assay for detection of genetically diverseFrontiers in microbiology · 2026Article
- Article
- Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era.Acta pharmaceutica Sinica. B · 2022Review
- Integrative Longitudinal Analysis of Metabolic Phenotype and Microbiota Changes During the Development of Obesity.Frontiers in cellular and infection microbiology · 2021Article
- Article
- Bacteriophages in the Dairy Environment: From Enemies to Allies.Antibiotics (Basel, Switzerland) · 2017Review
- DetectingFrontiers in microbiology · 2017Article
- Evolution of microbiological analytical methods for dairy industry needs.Frontiers in microbiology · 2014Review
- Bacteriophages and dairy fermentations.Bacteriophage · 2012Article
- Lactococcal 936-type phages and dairy fermentation problems: from detection to evolution and prevention.Frontiers in microbiology · 2012Article
- Bacteriophages of lactic acid bacteria and their impact on milk fermentations.Microbial cell factories · 2011Review
- Direct Quantitative Detection and Identification of Lactococcal Bacteriophages from Milk and Whey by Real-Time PCR: Application for the Detection of Lactococcal Bacteriophages in Goat's Raw Milk Whey in France.International journal of microbiology · 2011Article
- The MG1363 and IL1403 laboratory strains of Lactococcus lactis and several dairy strains are diploid.Journal of bacteriology · 2010Article
- Flow cytometry applications in the food industry.Journal of industrial microbiology & biotechnology · 2009Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriophage infection in dairy fermentation constitutes a serious problem worldwide. We have studied bacteriophage infection in Lactococcus lactis by using the flow cytometer. The first effect of the infection of the bacterium is a change from cells in chains toward single cells. We interpret this change as a consequence of a cease in cell growth, while the ongoing cell divisions leave the cells as single cells. Late in the infection cycle, cells with low-density cell walls appear, and these cells can be detected on cytograms of light scatter versus, for instance, fluorescence of stained DNA. We describe a new method for detection of phage infection in Lactococcus lactis dairy cultures. The method is based on flow cytometric detection of cells with low-density cell walls. The method allows fast and early detection of phage-infected bacteria, independently of which phage has infected the culture. The method can be performed in real time and therefore increases the chance of successful intervention in the fermentation process.
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Registered trials
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