ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2007
A rose by any other name? The potential consequences of microglial heterogeneity during CNS health and disease.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed.
- Astrocytes as a target for therapeutic strategies in epilepsy: current insights.Frontiers in molecular neuroscience · 2023Review
- Photobiomodulation Attenuated Cognitive Dysfunction and Neuroinflammation in a Prenatal Valproic Acid-Induced Autism Spectrum Disorder Mouse Model.International journal of molecular sciences · 2022Article
- Oxytocin and microglia in the development of social behaviour.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Repetitive binge-like consumption based on the Drinking-in-the-Dark model alters the microglial population in the mouse hippocampus.Journal of integrative neuroscience · 2021Article
- IL-20R Activation via rIL-19 Enhances Hematoma Resolution through the IL-20R1/ERK/Nrf2 Pathway in an Experimental GMH Rat Pup Model.Oxidative medicine and cellular longevity · 2021Article
- Regional elevations in microglial activation and cerebral glucose utilization in frontal white matter tracts of rhesus monkeys following prolonged cocaine self-administration.Brain structure & function · 2019Article
- A comparison of hippocampal microglial responses in aged and young rodents following dependent and non-dependent binge drinking.International review of neurobiology · 2019Article
- Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation.Frontiers in neuroscience · 2019Review
- Increased expression of M1 and M2 phenotypic markers in isolated microglia after four-day binge alcohol exposure in male rats.Alcohol (Fayetteville, N.Y.) · 2017Article
- Cellular and Molecular Identity of Tumor-Associated Macrophages in Glioblastoma.Cancer research · 2017Article
- Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes.Scientific reports · 2017Article
- Multitasking Microglia and Alzheimer's Disease: Diversity, Tools and Therapeutic Targets.Journal of molecular neuroscience : MN · 2016Review
- Microglia and Monocyte-Derived Macrophages in Stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2016Review
- Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophages.Journal of neuroinflammation · 2016Article
- Microglial activation induces neuronal death in Chandipura virus infection.Scientific reports · 2016Article
- Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders.Frontiers in cellular neuroscience · 2016Review
- Imaging robust microglial activation after lipopolysaccharide administration in humans with PET.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Functional differences between microglia and monocytes after ischemic stroke.Journal of neuroinflammation · 2015Article
- Impact of age-related neuroglial cell responses on hippocampal deterioration.Frontiers in aging neuroscience · 2015Review
- Relevance of Neuroinflammation and Encephalitis in Autism.Frontiers in cellular neuroscience · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Microglial activation and macrophage infiltration into the CNS are common features of CNS autoimmune disease and of chronic neurodegenerative diseases. Because these cells largely express an overlapping set of common macrophage markers, it has been difficult to separate their respective contributions to disease onset and progression. This problem is further confounded by the many types of macrophages that have been termed microglia. Several approaches, ranging from molecular profiling of isolated cells to the generation of irradiation chimeric rodent models, are now beginning to generate rudimentary definitions distinguishing the various types of microglia and macrophages found within the CNS and the potential roles that these cells may play in health and disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.