ArticleJournal of theoretical biology2007
Sperm competition can drive a male-biased mutation rate.
Article in Journal of theoretical biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Controlling for life-history traits in vertebrates reveals that effective population size does not affect mutation rate or genome size.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Characterization and distribution of de novo mutations in the zebra finch.Communications biology · 2024Article
- Coevolution of longevity and female germline maintenance.Proceedings. Biological sciences · 2024Article
- Increased male investment in sperm competition results in reduced maintenance of gametes.PLoS biology · 2023Article
- Article
- Experimental evidence for effects of sexual selection on condition-dependent mutation rates.Nature ecology & evolution · 2020Article
- Variable Autosomal and X Divergence Near and Far from Genes Affects Estimates of Male Mutation Bias in Great Apes.Genome biology and evolution · 2016Article
- Intralocus sexual conflict resolved through gene duplication.Trends in ecology & evolution · 2011Article
- Sperm competition selects for sperm quantity and quality in the Australian Maluridae.PloS one · 2011Article
- Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila.Genome biology and evolution · 2010Article
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Authors and funding
1 author.
Funding
Abstract
A pattern of male-biased mutation has been found in a wide range of species. The standard explanation for this bias is that there are greater numbers of mitotic cell divisions in the history of the average sperm, compared to the average egg, and that mutations typically result from errors made during replication. However, this fails to provide an ultimate evolutionary explanation for why the male germline would tolerate more mutations that are typically deleterious. One possibility is that if there is a tradeoff between producing large numbers of sperm and expending energetic resources in maintaining a lower mutation rate, sperm competition would select for males that produce larger numbers of sperm despite a higher resulting mutation rate. Here I describe a model that jointly considers the fitness consequences of deleterious mutation and mating success in the face of sperm competition. I show that a moderate level of sperm competition can account for the observation that the male germline tolerates a higher mutation rate than the female germline.
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