ReviewNeurochemical research1991
How peptidergic neurons cope with variation in physiological stimulation.
Review in Neurochemical research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 16 citations in OpenAlex.
- Alterations in ZENK and glucagon RNA transcript expression during increased ocular growth in chickens.Molecular vision · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A general scheme for neuropeptide metabolism is outlined and the potential sites of regulation are discussed. Two major sites of regulation are distinguished: transcription which ultimately limits the rate of translation to form the prepropeptide, and post-translational processing steps. The consequences of up-regulation of these steps in response to increased metabolic demand are discussed. An alternative strategy for peptidergic neurons, reliance on a large pool of neuropeptide, is proposed. Data on the response of enkephalin-containing cells to increased levels of stimulation are reviewed. It is concluded that there is good evidence for genomic up-regulation, perhaps in association with regulation of processing. Evidence based on studies on enkephalin-containing amacrine cells in the chicken retina is also reviewed. It is suggested that these cells rely on a large pool of neuropeptide to cope with changes in demand.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.