ArticleNeurochemical research1991
Expression of actin and myosin genes during PC12 cell differentiation.
Article in Neurochemical research, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed, 9 citations in OpenAlex.
- Induction of neuron-specific tropomyosin mRNAs by nerve growth factor is dependent on morphological differentiation.The Journal of cell biology · 1993Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have measured the accumulation of transcripts for myosin and actin during NGF induced differentiation of PC12 cells. Beta (beta) and gamma (gamma) actin and myosin light chains (MLC) 2 and 3 show different patterns of expression, with transient elevations in gene expression one day after NGF addition. This elevation occurs earlier than that of neurite outgrowth, neurofilament protein (NF68) (16) and Thy-1 glycoprotein gene expression. These results suggest differing mechanisms of control of actin and myosin expression, together with a varying function and relationship between them during NGF-induced neurite differentiation.
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Registered trials
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