Evidence map›Paper›PMID 17919126›Full record

ReviewBrain pathology (Zurich, Switzerland)2007

The role of the neurobiologist in redefining the diagnosis of autism.

Eric London

Abstract readReview
In one paragraph

Review in Brain pathology (Zurich, Switzerland), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Toward Equity in Research on Intellectual and Developmental Disabilities.American journal on intellectual and developmental disabilities · 2023
    Article
  2. Review
  3. Prototyping as subtyping strategy for studying heterogeneity in autism.Autism research : official journal of the International Society for Autism Research · 2021
    Article
  4. Review
  5. Article
  6. Goldenhar syndrome: current perspectives.World journal of pediatrics : WJP · 2017
    Review
  7. Article
  8. Article
  9. Mouse models of autism: testing hypotheses about molecular mechanisms.Current topics in behavioral neurosciences · 2011
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Eric LondonDepartment of Psychology, Institute for Basic Research in Developmental Disabilities, Staten Island, NY, USA. naarlondon@gmail.com

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until recently, autism, along with the other developmental disabilities, was largely ignored by the medical and research community. At this early point in our understanding of the syndrome, neurobiologists and especially those who work with human brain tissue have a great deal to offer. A thorough understanding of the clinically defined syndrome is essential. Along with the other psychiatric diseases listed in the Diagnostic and Statistical Manual of Mental Disorders (DSM), autism is defined by gross behavioral macros that, in all probability, are only indirectly related to basic biological systems. The diagnostic schema is not etiologically based. The diagnostic triad of symptoms that defines autism--impaired communication, impaired social interaction, and restricted and repetitive interests and activities--has been found to be present in the general population with no clear demarcation between pathological severity and being a common trait. In addition, the three basic symptoms of autism appear not to associate highly, thus leaving undetermined the validity of studying autism in its currently defined triad of symptoms. It is proposed that a close working relationship between neurobiologists and clinicians is necessary in order to identify etiologically based diagnostic schemas that would complement, rather than replace, the clinical diagnosis.

Indexed as

Autistic DisorderBiomedical ResearchBrainChildDiagnosis, DifferentialHumansInheritance PatternsInterdisciplinary CommunicationNeurologyNeurosciencesSocial Behavior Disorders

Identifiers

PMID17919126
PMCPMC8095627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.