Evidence map›Paper›PMID 17919114›Full record

ArticleJournal of perinatal medicine2007

Resistin: a hormone which induces insulin resistance is increased in normal pregnancy.

Jyh Kae Nien, Shali Mazaki-Tovi, Roberto Romero, Juan Pedro Kusanovic, Offer Erez, Francesca Gotsch, Beth L Pineles, Lara A Friel, Jimmy Espinoza, Luis Goncalves and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of perinatal medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
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  5. Review
  6. Article
  7. Article
  8. Polycystic Ovarian Syndrome (PCOS): Does the Challenge End at Conception?International journal of environmental research and public health · 2022
    Review
  9. Article
  10. Article
  11. Adiponectin as a Potential Biomarker for Pregnancy Disorders.International journal of molecular sciences · 2021
    Review
  12. The Role of the Adipokines in the Most Common Gestational Complications.International journal of molecular sciences · 2020
    Review
  13. Intimate Partner Violence: A Risk Factor for Gestational Diabetes.International journal of environmental research and public health · 2020
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Maternal and neonatal circulating visfatin concentrations in patients with pre-eclampsia and a small-for-gestational age neonate.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2010
    Article
  20. Could alterations in maternal plasma visfatin concentration participate in the phenotype definition of preeclampsia and SGA?The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Jyh Kae NienPerinatology Research Branch, Intramural Division, NICHD/NIH/DHHS, Hutzel Women's Hospital, Bethesda, MD, USA.
Shali Mazaki-Tovi
Roberto Romero
Juan Pedro Kusanovic
Offer Erez
Francesca Gotsch
Beth L Pineles
Lara A Friel
Jimmy Espinoza
Luis Goncalves
Joaquin Santolaya
Ricardo Gomez
Joon-Seok Hong
Samuel Edwin
Eleazar Soto
Karina Richani
Moshe Mazor
Sonia S Hassan
Hutzel Women's Hospital · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USWayne State University · USBen-Gurion University of the Negev · IL

Funding

THE ROLE OF SUBCLINICAL INFECTION AND CYTOKINES IN PRETERM PARTURITIONZ01HD002400 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROMERO, ROBERTO · 1992 to 2008
$8.2M
Intramural NIH HHS Z01 HD002400
6 · The paper itself

Abstract

aimsResistin, a newly discovered adipokine, is thought to play a key role in the regulation of insulin resistance. The objectives of this study were to develop a nomogram of maternal plasma concentrations of resistin from 11 weeks of gestation to term and to determine whether resistin concentrations differ between normal and overweight pregnant women.

methodsIn this cross-sectional study, plasma concentrations of resistin were determined in normal pregnant women of normal body mass index (BMI 18.5-24.9; n=261), overweight pregnant women (BMI > or =25; n=140), and non-pregnant women of normal BMI (n=40). Blood samples were collected once from each woman between the first trimester and term. Percentiles for resistin concentration were determined for five pre-specified windows of gestational age. Plasma resistin concentration was determined by immunoassay. Non-parametric statistics were used for analysis.

resultsThe median maternal plasma concentration of resistin between 11 to 14 weeks of gestation in women of normal weight was significantly higher than non-pregnant women; the plasma concentration of resistin increased with gestational age.

conclusionsNormal pregnant women have a higher median plasma concentration of resistin than non-pregnant women and the concentration of this adipokine increases with advancing gestation. Alterations in the maternal plasma concentration of resistin during pregnancy could contribute to metabolic changes of pregnancy.

Indexed as

AdultBody Mass IndexCross-Sectional StudiesFemaleGestational AgeHumansInsulin ResistanceNomogramsPregnancyResistinResistin

Identifiers

PMID17919114
PMCPMC2413054
OpenAlexW2095153023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.