ArticleScandinavian journal of gastroenterology2007
Is there an association between coeliac disease and inflammatory bowel diseases? A study of relative prevalence in comparison with population controls.
Article in Scandinavian journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- Defining the optimum strategy for identifying adults and children with coeliac disease: systematic review and economic modelling.Health technology assessment (Winchester, England) · 2022Pooled it
- Celiac Disease Is Associated with Microscopic Colitis in Refractory Cases in Adults: A Systematic Review and Meta-Analysis of Observational Studies.Digestive diseases and sciences · 2022Pooled it
- Pooled it
- Review
- The Gluten-Free Diet for Celiac Disease: Critical Insights to Better Understand Clinical Outcomes.Nutrients · 2023Review
- Dietary Exposures and Interventions in Inflammatory Bowel Disease: Current Evidence and Emerging Concepts.Nutrients · 2023Review
- Causal association between celiac disease and inflammatory bowel disease: A two-sample bidirectional Mendelian randomization study.Frontiers in immunology · 2022Article
- Guidelines for the management of patients with Crohn's disease. Recommendations of the Polish Society of Gastroenterology and the Polish National Consultant in Gastroenterology.Przeglad gastroenterologiczny · 2021Article
- Prevalence of Celiac Disease in Children and Adolescents With Inflammatory Bowel Disease.Cureus · 2020Article
- Practical clinical approach to the evaluation of hepatobiliary disorders in inflammatory bowel disease.Frontline gastroenterology · 2019Review
- Prevalance of Celiac Disease in Patients with Inflammatory Bowel Disease in Turkish Population.Gastroenterology research and practice · 2019Article
- HLA-DQ: Celiac diseaseWorld journal of gastroenterology · 2018Observational
- Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases.World journal of gastroenterology · 2017Article
- The impact of co-existing immune-mediated diseases on phenotype and outcomes in inflammatory bowel diseases.Alimentary pharmacology & therapeutics · 2017Article
- Prevalence of inflammatory bowel disease among coeliac disease patients in a Hungarian coeliac centre.BMC gastroenterology · 2015Article
- Assessing of Celiac Disease and Nonceliac Gluten Sensitivity.Gastroenterology research and practice · 2015Review
- Prevalence of a gluten-free diet and improvement of clinical symptoms in patients with inflammatory bowel diseases.Inflammatory bowel diseases · 2014Article
- Impact of coexistent celiac disease on phenotype and natural history of inflammatory bowel diseases.The American journal of gastroenterology · 2013Article
- Human leukocyte antigen DQ2/8 prevalence in non-celiac patients with gastrointestinal diseases.World journal of gastroenterology · 2013Article
- Celiac disease in a child with ulcerative colitis: a possible genetic association.Journal of clinical gastroenterology · 2013Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe relationship between coeliac disease and inflammatory bowel disease (IBD) is controversial. The aim of this study was to determine the prevalence of coeliac disease in IBD and the prevalence of IBD in coeliac disease. MATERIAL AND
methodsPatients were enrolled from specialist IBD and coeliac clinics. Antigliadins, endomysial, tissue transglutaminase antibody and total IgA levels were measured in IBD patients. Patients with positive antibodies were offered a duodenal biopsy. The notes on coeliac patients were reviewed for colonoscopic and biopsy findings. Controls were recruited from the local population.
resultsThe study included 305 patients with coeliac disease, 354 with IBD and 601 healthy controls. The IBD group comprised 154 ulcerative colitis (UC) cases, 173 Crohn's disease, 18 indeterminate colitis and 9 cases of microscopic colitis. Forty-seven patients had positive antibodies and 3 had villous atrophy on biopsy. All three patients had positive anti-tissue transglutaminase antibodies but only two were endomysial antibody (EMA) positive. Ten coeliac patients had IBD (5 UC and 5 lymphocytic colitis). Five controls had coeliac disease and 2 had IBD (1 Crohn's disease and 1 UC). Stepwise multiple logistic regression showed only antibody positivity as being significant (p<0.0001).
conclusionsThe prevalence of IBD in coeliac disease was increased 10-fold compared with that in controls (odds ratio 9.98, 95% CI 2.8-45.9, p=0.0006), while the prevalence of coeliac disease in IBD was comparable with that in controls (odds ratio 1.02, 95% CI, 0.24-4.29, p=1.0).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.