Evidence map›Paper›PMID 17917771›Full record

ArticleWorld journal of surgery2007

Surgical site infection among women discharged with a drain in situ after breast cancer surgery.

Wilza Andrade Barbosa Felippe, Guilherme Loureiro Werneck, Guilherme Santoro-Lopes

2 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in World journal of surgery, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03229824 nacompletednot on this mapstarted 2016, after this paper: background citation

Randomized Controlled Trial to Reduce Surgical Site Infections in Breast Cancer Surgery With Clorhexidine Gluconate Securement Dressing (Tegaderm CHG)

TypeinterventionalSponsorNational Institute of CancerologíaRan2016 to 2018Enrolled116ConditionsBreast CancerArmsAntiseptic occlusive dressing group
NCT04577846 phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

Surgical Site Infection (SSI) Rates in Patients Undergoing Mastectomy Without Reconstruction, a Comparison Among Those Receiving Preoperative Prophylactic Antibiotics Alone Versus Continued Prophylactic Antibiotics Postoperatively-A Multicenter, Double-blinded Randomized Control Trial.

TypeinterventionalSponsorAga Khan UniversityRan2020 to 2022Enrolled384ConditionsSurgical Site InfectionArmsCephalexin 500 MG, Placebo
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wilza Andrade Barbosa FelippeHospital do Cancer III, Instituto Nacional do Cancer, Rio de Janeiro, Brazil.
Guilherme Loureiro Werneck
Guilherme Santoro-Lopes
Universidade Federal do Rio de Janeiro · BRInstituto Nacional do Câncer · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are scarce data on the factors associated with surgical site infection (SSI) among women who are discharged with a drain in situ after breast cancer surgery. The aim of this study was to determine the incidence and the factors associated with SSI in a center where women are routinely discharged with a drain in place.

methodsA prospective cohort study included 354 women who underwent surgical treatment for breast cancer at a referral center in Rio de Janeiro, Brazil.

resultsSSI was diagnosed in 60 patients (17%) after a median follow-up of 17 days. Most infections were caused by Staphylococcus aureus. The probability of bacterial colonization of the drain was 33% on postoperative day (POD) 7 and rose to 80.8% up to the POD 14. In 83% of the cases of microbiologically documented infection, SSI was caused by the same bacterial species that had been previously isolated from the drainage fluid. In multivariate regression analyses, age 50 years (p < 0.001), skin flap necrosis (p < 0.001), and bacterial colonization of the drain (p = 0.03) were independently associated with a higher incidence of SSI.

conclusionThe incidence of SSI among women who were routinely discharged with a drain in place was high. Older age, skin flap necrosis, and bacterial colonization of the drain were independent predictors of SSI. Modifications of the surgical technique aimed at reducing the risk of wound necrosis and early removal of the drain may contribute to lowering the risk of SSI among these patients.

Indexed as

Antibiotic ProphylaxisBreast NeoplasmsDrainageFemaleHumansIncidenceLymph Node ExcisionMastectomyMiddle AgedPatient DischargePostoperative CareProspective StudiesRisk FactorsSurgical Wound InfectionTime Factors

Identifiers

PMID17917771
OpenAlexW2089227213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.