Evidence map›Paper›PMID 17917657›Full record

ArticleNature medicine2007

Not so fast: adaptive suppression of innate immunity.

Noah W Palm, Ruslan Medzhitov

Abstract readNewsComment
In one paragraph

Article in Nature medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Identification of KeyInternational journal of molecular sciences · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. COVID-19 and diabetes: Association intensify risk factors for morbidity and mortality.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Aging-induced fragility of the immune system.Journal of theoretical biology · 2021
    Article
  17. Review
  18. Review
  19. Diabetes and COVID-19.Open life sciences · 2021
    Review
  20. T Cells: Warriors of SARS-CoV-2 Infection.Trends in immunology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Noah W Palm
Ruslan Medzhitov

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunity, ActiveImmunity, InnateAnimalsHistocompatibility Antigens Class IIInterferon-gammaMiceMice, Mutant StrainsMice, NudeModels, ImmunologicalPoly I-CT-LymphocytesT-Lymphocytes, RegulatoryToll-Like Receptor 3Tumor Necrosis Factor-alphaHistocompatibility Antigens Class IIInterferon-gammaPoly I-CTLR3 protein, mouseToll-Like Receptor 3Tumor Necrosis Factor-alpha

Identifiers

PMID17917657
PMCPMC7095835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.