ReviewMolecular neurobiology2007
Ionic channel function in action potential generation: current perspective.
Review in Molecular neurobiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 62 citations in OpenAlex.
- Plasticity in thoracic paravertebral sympathetic postganglionic neurons after high spinal cord transection.bioRxiv : the preprint server for biology · 2025Article
- Evaluation of Small-Molecule Candidates as Modulators of M-Type KInternational journal of molecular sciences · 2025Review
- Classifying Neuronal Cell Types Based on Shared Electrophysiological Information from Humans and Mice.Neuroinformatics · 2024Article
- Tetrodotoxin-resistant mechanosensitivity and L-type calcium channel-mediated spontaneous calcium activity in enteric neurons.Experimental physiology · 2024Article
- Alfaxalone does not have long-term effects on goldfish pyramidal neuron action potential properties or GABAFEBS open bio · 2024Article
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- Mechanism of Pacemaker Activity in Zebrafish DC2/4 Dopaminergic Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Delta-opioid receptor-mediated modulation of excitability of individual hippocampal neurons: mechanisms involved.Pharmacological reports : PR · 2021Article
- Secondhand Smoke Decreased Excitability and Altered Action Potential Characteristics of Cardiac Vagal Neurons in Mice.Frontiers in physiology · 2021Article
- Stereotactically Injected Kv1.2 and CASPR2 Antisera Cause Differential Effects on CA1 Synaptic and Cellular Excitability, but Both Enhance the Vulnerability to Pro-epileptic Conditions.Frontiers in synaptic neuroscience · 2020Article
- Ionic mechanisms underlying history-dependence of conduction delay in an unmyelinated axon.eLife · 2017Article
- Important modifications by sugammadex, a modified γ-cyclodextrin, of ion currents in differentiated NSC-34 neuronal cells.BMC neuroscience · 2017Article
- Transient BK outward current enhances motoneurone firing rates during Drosophila larval locomotion.The Journal of physiology · 2015Article
- Neuromodulation of neurons and synapses.Current opinion in neurobiology · 2014Review
- Activation of 5-HT2A receptors by TCB-2 induces recurrent oscillatory burst discharge in layer 5 pyramidal neurons of the mPFC in vitro.Physiological reports · 2014Article
- Voltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration.Translational stroke research · 2014Review
- A fast BK-type KCa current acts as a postsynaptic modulator of temporal selectivity for communication signals.Frontiers in cellular neuroscience · 2014Article
- Vasoactive intestinal peptide produces long-lasting changes in neural activity in the suprachiasmatic nucleus.Journal of neurophysiology · 2013Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over 50 years ago, Hodgkin and Huxley laid down the foundations of our current understanding of ionic channels. An impressive progress has been made during the following years that culminated in the revelation of the details of potassium channel structure. Nevertheless, even today, we cannot separate well currents recorded in central mammalian neurons. Many modern concepts about the function of sodium and potassium currents are based on experiments performed in nonmammalian cells. The recent recognition of the fast delayed rectifier current indicates that we need to reevaluate the biophysical role of sodium and potassium currents. This review will consider high quality voltage clamp data obtained from the soma of central mammalian neurons in the view of our current knowledge about proteins forming ionic channels. Fast sodium currents and three types of outward potassium currents, the delayed rectifier, the subthreshold A-type, and the D-type potassium currents, are discussed here. An updated current classification with biophysical role of each current subtype is provided. This review shows that details of kinetics of both sodium and outward potassium currents differ significantly from the classical descriptions and these differences may be of functional significance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.