ReviewImmunologic research2007
Common variable immune deficiency: reviews, continued puzzles, and a new registry.
Review in Immunologic research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Genomic and clinical characterization of adult CVID patients: results from a single-centre turkish cohort.Immunologic research · 2025Article
- Review
- Infection Phenotypes Among Patients with Primary Antibody Deficiency Mined from a US Patient Registry.Journal of clinical immunology · 2021Article
- The Importance of Primary Immune Deficiency Registries: The United States Immunodeficiency Network Registry.Immunology and allergy clinics of North America · 2020Review
- Treatment of patients with immune thrombocytopenia admitted to the emergency room.International journal of hematology · 2016Article
- Expression of essential B cell development genes in horses with common variable immunodeficiency.Molecular immunology · 2012Article
- Regulation of mucosal IgA responses: lessons from primary immunodeficiencies.Annals of the New York Academy of Sciences · 2011Review
- Immunoglobulin responses at the mucosal interface.Annual review of immunology · 2011Review
- Innate signals in mucosal immunoglobulin class switching.The Journal of allergy and clinical immunology · 2010Review
- Adult-onset presentations of genetic immunodeficiencies: genes can throw slow curves.Current opinion in infectious diseases · 2010Review
- Serum bactericidal antibody response 1 year after meningococcal polysaccharide vaccination of patients with common variable immunodeficiency.Clinical and vaccine immunology : CVI · 2010Article
- Immunodeficiencies.Clinical and experimental immunology · 2009Review
- A decreased frequency of regulatory T cells in patients with common variable immunodeficiency.PloS one · 2009Article
- Common variable immunodeficiency in horses is characterized by B cell depletion in primary and secondary lymphoid tissues.Journal of clinical immunology · 2009Article
- Proinflammatory cytokine gene single nucleotide polymorphisms in common variable immunodeficiency.Clinical and experimental immunology · 2009Article
- The biology of intestinal immunoglobulin A responses.Immunity · 2008Review
- The regulation of IgA class switching.Nature reviews. Immunology · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundCommon variable immune deficiency (CVID) is a clinically and immunologically heterogenous primary immune deficiency first described more than 50 years ago. The main features are hypogammaglobulinemia, recurrent infections, and other complications. While CVID is considered as a genetic immune defect, and several genes have been reported as leading to the CVID phenotype, one of the most puzzling features of CVID is the sporadic inheritance pattern and the relatively late onset. In most cases, no other family members have any immune defect. The mean age at diagnosis is between 25 and 45 years of age. These features suggest the interplay between either several or numerous genes with or without potential environmental factors.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.