ArticleBiological psychiatry2008
Nonverbal delayed recognition in the relatives of schizophrenia patients with or without schizophrenia spectrum.
Article in Biological psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- MICEmi: A method to identify cognitive endophenotypes of mental illnesses.European psychiatry : the journal of the Association of European Psychiatrists · 2022Review
- The Prediction Analysis of Autistic and Schizotypal Traits in Attentional Networks.Psychiatry investigation · 2021Article
- Opposite Cannabis-Cognition Associations in Psychotic Patients Depending on Family History.PloS one · 2016Article
- Discrimination within Recognition Memory in Schizophrenia.Behavioral sciences (Basel, Switzerland) · 2013Article
- Reduced NMDAR1 expression in the Sp4 hypomorphic mouse may contribute to endophenotypes of human psychiatric disorders.Human molecular genetics · 2010Article
- Premorbid cognitive deficits in young relatives of schizophrenia patients.Frontiers in human neuroscience · 2010Article
- When doors of perception close: bottom-up models of disrupted cognition in schizophrenia.Annual review of clinical psychology · 2009Review
- Neurocognitive allied phenotypes for schizophrenia and bipolar disorder.Schizophrenia bulletin · 2008Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThere is increased interest in the study of cognitive deficits as possible endophenotypic markers for schizophrenia. The main goal of this study was to determine how familiality and schizophrenia spectrum personality symptomatology are related to performance of auditory and visuospatial delayed recognition memory tasks.
methodsThe study sample consisted of 162 subjects divided into five groups. The groups included 39 patients with a DSM-IV diagnosis of schizophrenia or schizophreniform disorder; first-degree relatives of schizophrenia patients, 22 with and 31 without schizophrenia spectrum personality traits; and healthy control subjects with no family history of psychosis, 22 with and 48 without schizophrenia spectrum traits. Auditory and visuospatial delayed recognition memory performance was assessed.
resultsSignificant differences were observed between patients and healthy control subjects in both auditory [F(1,79) = 7.358 p = .008] and visual [F(1,47) = 34.67, p < .001] delayed recognition tasks. When comparing the four non-patient groups, auditory and visuospatial discriminability decreased as a function of familiality of schizophrenia (p < .05). Deficits were more pronounced in relatives with schizophrenia spectrum traits [auditory d = .7114; visual d = 1.0199].
conclusionsA biological relationship to schizophrenia increases the likelihood of impaired delayed recognition memory. Likewise, poorer performance is associated with schizophrenia spectrum phenotype only when combined with familiality.
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