ArticleCell stress & chaperones2007
Developmentally regulated synthesis of p8, a stress-associated transcription cofactor, in diapause-destined embryos of Artemia franciscana.
Article in Cell stress & chaperones, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- NUPR1 in breast cancer: mechanisms and potential applications.Frontiers in physiology · 2026Review
- Article
- Effect of Different Culture Conditions on Gene Expression Associated With Cyst Production in Populations ofFrontiers in genetics · 2022Article
- Mechanisms of Desiccation Tolerance: Themes and Variations in Brine Shrimp, Roundworms, and Tardigrades.Frontiers in physiology · 2020Review
- The transcription factor p8 regulates autophagy during diapause embryo formation in Artemia parthenogenetica.Cell stress & chaperones · 2016Article
- Study of model systems to test the potential function of Artemia group 1 late embryogenesis abundant (LEA) proteins.Cell stress & chaperones · 2016Article
- Expression and roles of As-NUPR1 protein from Artemia sinica during embryo development and in response to salinity stress.Molecular biology reports · 2014Article
- Biotic acts of antibiotics.Frontiers in microbiology · 2013Article
- Comparative studies on sorting cells from Artemia sinica at different developmental stages for in vitro cell culture.In vitro cellular & developmental biology. Animal · 2011Article
- In silico cloning and characterization of p8 homolog cDNA from common urchin (Paracentrotus lividus).Molecular biology reports · 2009Article
- Embryonic diapause highlighted by differential expression of mRNAs for ecdysteroidogenesis, transcription and lipid sparing in the cricket Allonemobius socius.The Journal of experimental biology · 2009Article
- Activation of an AMP-activated protein kinase is involved in post-diapause development of Artemia franciscana encysted embryos.BMC developmental biology · 2009Article
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2 authors.
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Abstract
Diapause-destined embryos of the crustacean Artemia franciscana arrest as gastrulae, acquire extreme stress tolerance, and enter profound metabolic dormancy. Among genes upregulated at 2 days postfertilization in these embryos is a homologue of p8, a stress-inducible transcription cofactor. Artemia p8 is smaller than vertebrate homologues but shares a basic helix-loop-helix domain and a bipartite nuclear localization signal. Probing of restriction digested DNA on Southern blots indicated a single Artemia p8 gene and 5'-RACE specified 2 transcription start sites. Several putative cis-acting regulatory sequences, including two heat shock elements, appeared upstream of the p8 transcription start site. Artemia p8 mRNA increased sharply at 1 day postfertilization in diapause-destined embryos and then declined, whereas p8 protein appeared 2 days postfertilization and remained relatively constant throughout development, indicating a stable protein. p8 was not detectable in nauplius-destined (nondiapause) Artemia embryos. Immunofluorescent staining revealed p8 within Artemia nuclei. The results support the idea that p8, a known stressresponsive transcription cofactor, mediates gene expression in diapause-destined Artemia embryos. p8 is the first diapause-related transcription factor identified in crustaceans and 1 of only a small number of such proteins identified in any organism undergoing diapause.
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