Evidence map›Paper›PMID 17915311›Full record

ReviewBiomaterials2007

Muscle-derived stem cells for tissue engineering and regenerative therapy.

Arvydas Usas, Johnny Huard

Open access · greenAbstract readReview
In one paragraph

Review in Biomaterials, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 160 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Stem Cell and Macrophage Roles in Skeletal Muscle Regenerative Medicine.International journal of molecular sciences · 2021
    Review
  17. Article
  18. Current Strategies for the Regeneration of Skeletal Muscle Tissue.International journal of molecular sciences · 2021
    Review
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Arvydas UsasStem Cell Research Center, Department of Orthopedic Surgery, Children's Hospital of Pittsburgh, Pittsburgh, PA 15213, USA.
Johnny Huard
Children's Hospital of Pittsburgh · US

Funding

Preclinical Gene Therapy in a Large Animal Model of DMDU54AR050733 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GLORIOSO, JOSEPH C · 2003 to 2008
$7.7M
Muscle Based Tissue Engineering to Improve Bone HealingR01DE013420 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUARD, JOHNNY · 2001 to 2010
$3.6M
Muscle regeneration through stem cell transplantationR01AR049684 · NIAMS · CHILDREN'S HOSP PITTSBURGH/UPMC HLTH SYS · PI HUARD, JOHNNY · 2002 to 2006
$1.4M
NIAMS NIH HHS R01 AR049684NIAMS NIH HHS U54 AR050733NIDCR NIH HHS R01 DE013420
6 · The paper itself

Abstract

Skeletal muscle has been recognized as an essential source of progenitor or satellite cells, which are primarily responsible for muscle regeneration. Recently, muscle has also been identified as a valuable source of postnatal stem cells that appear to be distinct from satellite cells and possess the ability to differentiate into other cell lineages. These cells, named muscle-derived stem cells, possess a high myogenic capacity and effectively regenerate both skeletal and cardiac muscle. Remarkably, when genetically modified ex vivo to express growth factors, these cells can differentiate into osteogenic and chondrogenic lineages and have been shown to promote the repair of bone and cartilage. Muscle stem cell-based regenerative therapy and tissue engineering using ex vivo gene therapy, are promising approaches for the treatment of various musculoskeletal, cardiovascular, and urological disorders.

Indexed as

AnimalsBone and BonesCartilageHumansMusclesRegenerative MedicineStem CellsTissue Engineering

Identifiers

PMID17915311
PMCPMC2095130
OpenAlexW2149325776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.