Evidence map›Paper›PMID 17915034›Full record

ArticleGenome biology2007

Finding disease candidate genes by liquid association.

Ker-Chau Li, Aarno Palotie, Shinsheng Yuan, Denis Bronnikov, Daniel Chen, Xuelian Wei, Oi-Wa Choi, Janna Saarela, Leena Peltonen

Abstract readComparative Study
In one paragraph

Article in Genome biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Network Modeling in Biology: Statistical Methods for Gene and Brain Networks.Statistical science : a review journal of the Institute of Mathematical Statistics · 2021
    Article
  4. Article
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  6. Article
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  8. Detecting subnetwork-level dynamic correlations.Bioinformatics (Oxford, England) · 2017
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ker-Chau LiDepartment of Statistics, UCLA, 8125 Math Sciences Bldg, Los Angeles, California 90095-1554, USA. kcli@stat.ucla.edu
Aarno Palotie
Shinsheng Yuan
Denis Bronnikov
Daniel Chen
Xuelian Wei
Oi-Wa Choi
Janna Saarela
Leena Peltonen

Funding

Genetic loci predisposing to multiple sclerosis (MS)R01NS043559 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PELTONEN, LEENA · 2002 to 2005
$984k
NINDS NIH HHS R01 NS043559NINDS NIH HHS R01 NS 43559
6 · The paper itself

Abstract

A novel approach to finding candidate genes by using gene expression data through liquid association is developed and used to identify multiple sclerosis susceptibility candidate genes.

Indexed as

Gene ExpressionComputational BiologyExcitatory Amino Acid Transporter 1FinlandGenetic Predisposition to DiseaseGenetic TestingGenomicsGenotypeHumansMultiple SclerosisProtein Kinase C-alphaExcitatory Amino Acid Transporter 1PRKCA protein, humanProtein Kinase C-alphaSLC1A3 protein, human

Identifiers

PMID17915034
PMCPMC2246280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.