ArticleSleep2007
Gender differences in morbidity and health care utilization among adult obstructive sleep apnea patients.
Article in Sleep, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Upper airway stimulation vs other upper airway surgical procedures for OSA: a meta-analysis.Sleep & breathing = Schlaf & Atmung · 2022Pooled it
- Association between obstructive sleep apnea and health-related quality of life in untreated adults: a systematic review.Sleep & breathing = Schlaf & Atmung · 2021Pooled it
- Female predominance in nocturnal hypoxemia among elderly OSAS patients: hemoglobin mediates sex-specific hypoxic burden in Chinese cohorts.BMC geriatrics · 2025Article
- Sex and age differences in sleep disorders: insights from a diverse cohort referred to a sleep center.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Obstructive Sleep Apnea in Pediatrics and Adolescent Women: A Systematic Review of Sex-Based Differences Between Girls and Boys.Children (Basel, Switzerland) · 2024Review
- Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea.JAMA network open · 2024Article
- Sex-specific dementia risk in known or suspected obstructive sleep apnea: a 10-year longitudinal population-based study.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Sex Differences in 90-Day Functional Outcomes for Acute Ischemic Stroke Patients With Obstructive Sleep Apnea.Cureus · 2023Article
- Fifteen Patients Who Can Be Helped by Medicare: Insurance Policy Changes in the Coverage of CPAP Therapy for Obstructive Sleep Apnea.Neurology. Clinical practice · 2023Article
- Comorbidities and quality of life in Australian men and women with diagnosed and undiagnosed high-risk obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Gender Issues in Obstructive Sleep Apnea.The Yale journal of biology and medicine · 2021Review
- Sex differences within symptom subtypes of mild obstructive sleep apnea.Sleep medicine · 2021Article
- Evaluation of Obstructive Sleep Apnea in Female Patients in Primary Care: Time for Improvement?Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021Review
- The Effect of Gender and Sex Hormones on Cardiovascular Disease, Heart Failure, Diabetes, and Atrial Fibrillation in Sleep Apnea.Frontiers in physiology · 2021Review
- The COVID-19 Lockdown and CPAP Adherence: The More Vulnerable Ones Less Likely to Improve Adherence?Nature and science of sleep · 2021Article
- Obesity and cardiovascular disease in women.International journal of obesity (2005) · 2020Review
- Greater health care utilization and cost associated with untreated sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Article
- Gender Differences in Obstructive Sleep Apnea: The Value of Sleep Questionnaires with a Separate Analysis of Cardiovascular Patients.Journal of clinical medicine · 2020Article
- Epidemiological characteristics of obstructive sleep apnea in a hospital-based historical cohort in Lebanon.PloS one · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectiveTo explore gender differences in morbidity and total health care utilization 5 years prior to diagnosis of obstructive sleep apnea (OSA).
designCase-control study; patients were recruited between January 2001 and April 2003.
settingTwo university-affiliated sleep laboratories. PATIENTS: 289 women (22-81 years) with OSA were matched with 289 men with OSA for age, body mass index (BMI), and apnea-hypopnea index (AHI). All OSA patients were matched 1:1 with healthy controls by age, geographic area, and primary physician. MEASUREMENTS AND
resultsWomen with OSA compared to men with OSA have lower perceived health status and Functional Outcomes of Sleep Questionnaire score (54.5% vs. 28.4%, P <0.05 and 67.5+/-21.4 vs. 76+/-20.1, P <0.05, respectively). Compared to men with OSA, women with OSA have higher risk of hypothyroidism (OR 4.7; 95% CI, 2.3-10) and arthropathy (OR 1.6, 95% CI, 1.1-2.2) and lower risk for CVD (OR 0.7; 95% CI, 0.5-0.91). Compared to controls, both women and men with OSA had 1.8 times higher 5-year total costs (P <0.0001). Compared to men with OSA, expenditures for women with OSA are 1.3 times higher (P <0.0001). The multiple logistic regression (adjusting for BMI, AHI) revealed that age (OR 1.04; 95% CI, 1.01-1.07), antipsychotic and anxiolytic drugs (OR 2.3; 95% CI, 1.2-4.4), and asthma (OR 2.4; 95% CI, 1.1-5.6) are independent determinants for "most costly" OSA women.
conclusionCompared to men with similar OSA severity, women are heavier users of health care resources. Low FOSQ score and poor perceived health status in addition to overuse of psychoactive drugs are associated with high health care utilization among women with OSA.
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Registered trials
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