ArticleEuropean journal of applied physiology2007
Hyperoxia improves 20 km cycling time trial performance by increasing muscle activation levels while perceived exertion stays the same.
Article in European journal of applied physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Rapidity of responding to a hypoxic challenge during exercise.European journal of applied physiology · 2009Trial
- Mild hyperbaric oxygen therapy on subjective sleep quality, aerobic, anaerobic exercise test, brain and muscle tissue oxygenation response in Chinese University male athletes after muscle fatigue.BMC sports science, medicine & rehabilitation · 2026Article
- Effects of breathing a hyperoxic gas mixture on perceptual, biochemical and performance recovery following simulated soccer match play.Biology of sport · 2025Article
- Effects of mild hyperbaric oxygen therapy on timing sequence recovery of muscle fatigue in cJournal of exercise science and fitness · 2024Article
- Hyperoxia Improves Repeated-Sprint Ability and the Associated Training Load in Athletes.Frontiers in sports and active living · 2022Article
- Is Structured Exercise Performed with Supplemental Oxygen a Promising Method of Personalized Medicine in the Therapy of Chronic Diseases?Journal of personalized medicine · 2020Article
- Acute Low-Dose Hyperoxia during a Single Bout of High-Intensity Interval Exercise Does Not Affect Red Blood Cell Deformability and Muscle Oxygenation in Trained Men-A Randomized Crossover Study.Sports (Basel, Switzerland) · 2020Article
- The Effects of Hyperoxia on Sea-Level Exercise Performance, Training, and Recovery: A Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2018Review
- The Impact of Hyperoxia on Human Performance and Recovery.Sports medicine (Auckland, N.Z.) · 2017Review
- Hyperoxia Extends Time to Exhaustion During High-Intensity Intermittent Exercise: a Randomized, Crossover Study in Male Cyclists.Sports medicine - open · 2016Article
- Exposure to a combination of heat and hyperoxia during cycling at submaximal intensity does not alter thermoregulatory responses.Biology of sport · 2016Article
- Effect of Environmental and Feedback Interventions on Pacing Profiles in Cycling: A Meta-Analysis.Frontiers in physiology · 2016Review
- Lactate Contributes to Glyceroneogenesis and Glyconeogenesis in Skeletal Muscle by Reversal of Pyruvate Kinase.The Journal of biological chemistry · 2015Article
- Article
- Ventricular structure, function, and mechanics at high altitude: chronic remodeling in Sherpa vs. short-term lowlander adaptation.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Article
- Effects of exposure to normobaric hyperoxia on the recovery of local muscle fatigue in the quadriceps femoris of young people.Journal of physical therapy science · 2014Article
- Fatigue is a Brain-Derived Emotion that Regulates the Exercise Behavior to Ensure the Protection of Whole Body Homeostasis.Frontiers in physiology · 2012Article
- Is it time to retire the A.V. Hill Model?: A rebuttal to the article by Professor Roy Shephard.Sports medicine (Auckland, N.Z.) · 2011Article
- Pre-exposure to hyperoxic air does not enhance power output during subsequent sprint cycling.European journal of applied physiology · 2010Article
- Evidence for reverse flux through pyruvate kinase in skeletal muscle.American journal of physiology. Endocrinology and metabolism · 2009Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing inspiratory oxygen tension improves exercise performance. We tested the hypothesis that this is partly due to changes in muscle activation levels while perception of exertion remains unaltered. Eleven male subjects performed two 20-km cycling time-trials, one in hyperoxia (HI, FiO2 40%) and one in normoxia (NORM, FiO2 21%). Every 2 km we measured power output, heart rate, blood lactate, integrated vastus lateralis EMG activity (iEMG) and ratings of perceived exertion (RPE). Performance was improved on average by 5% in HI compared to NORM (P < 0.01). Changes in heart rate, plasma lactate concentration and RPE during the trials were similar. For the majority of the time-trials, power output was maintained in HI, but decreased progressively in NORM (P < 0.01) while it increased in both trials for the last kilometre (P < 0.0001). iEMG was proportional to power output and was significantly greater in HI than in NORM. iEMG activity increased significantly in the final kilometer of both trials (P < 0.001). This suggests that improved exercise performance in hyperoxia may be the result of increased muscle activation leading to greater power outputs. The finding of identical RPE, lactate and heart rate in both trials suggests that pacing strategies are altered to keep the actual and perceived exercise stress at a similar level between conditions. We suggest that a complex, intelligent system regulates exercise performance through the control of muscle activation levels in an integrative manner under conditions of normoxia and hyperoxia.
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Registered trials
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