ArticleEvolution; international journal of organic evolution2007
Evolution of host specificity drives reproductive isolation among RNA viruses.
Article in Evolution; international journal of organic evolution, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Species-specific barriers restrict virus spillover potential across the Caenorhabditis genus.PLoS biology · 2026Article
- Narrowed host ranges do not constrain future host range expansion in RNA phage Φ6.Journal of virology · 2026Article
- The Biology of Nucleus-Forming Jumbo Phages.Annual review of genetics · 2025Review
- Survival of Thermostable Φ6 Genotypes in Acidic, Basic, and UV Environments.bioRxiv : the preprint server for biology · 2025Article
- Spatial clustering of hosts can favor specialist parasites.Ecology and evolution · 2024Article
- Experimental Evolution Studies in Φ6 Cystovirus.Viruses · 2024Review
- Competition-driven eco-evolutionary feedback reshapes bacteriophage lambda's fitness landscape and enables speciation.Nature communications · 2024Article
- Temporal and coevolutionary analyses reveal the events driving the emergence and circulation of human mamastroviruses.Emerging microbes & infections · 2023Article
- Genetic Diversity among Rose Rosette Virus Isolates: A Roadmap towards Studies of Gene Function and Pathogenicity.Pathogens (Basel, Switzerland) · 2023Article
- Host prediction for disease-associated gastrointestinal cressdnaviruses.Virus evolution · 2022Article
- Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations.eLife · 2021Article
- Variable routes to genomic and host adaptation among coronaviruses.Journal of evolutionary biology · 2021Article
- Host diversity slows bacteriophage adaptation by selecting generalists over specialists.Nature ecology & evolution · 2021Article
- Viral speciation through subcellular genetic isolation and virogenesis incompatibility.Nature communications · 2021Article
- The Phage Nucleus and PhuZ Spindle: Defining Features of the Subcellular Organization and Speciation of Nucleus-Forming Jumbo Phages.Frontiers in microbiology · 2021Review
- Article
- Viral ecogenomics across the Porifera.Microbiome · 2020Article
- Profile of Paul E. Turner.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Experimental evolution for niche breadth in bacteriophage T4 highlights the importance of structural genes.MicrobiologyOpen · 2020Article
- Existing Host Range Mutations Constrain Further Emergence of RNA Viruses.Journal of virology · 2019Article
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Authors and funding
3 authors.
Funding
Abstract
Ecological speciation hypotheses claim that assortative mating evolves as a consequence of divergent natural selection for ecologically important traits. Reproductive isolation is expected to be particularly likely to evolve by this mechanism in species such as phytophagous insects that mate in the habitats in which they eat. We tested this expectation by monitoring the evolution of reproductive isolation in laboratory populations of an RNA virus that undergoes genetic exchange only when multiple virus genotypes coinfect the same host. We subjected four populations of the RNA bacteriophage phi6 to 150 generations of natural selection on a novel host. Although there was no direct selection acting on host range in our experiment, three of the four populations lost the ability to infect one or more alternative hosts. In the most extreme case, one of the populations evolved a host range that does not contain any of the hosts infectible by the wild-type phi6. Whole genome sequencing confirmed that the resulting reproductive isolation was due to a single nucleotide change, highlighting the ease with which an emerging RNA virus can decouple its evolutionary fate from that of its ancestor. Our results uniquely demonstrate the evolution of reproductive isolation in allopatric experimental populations. Furthermore, our data confirm the biological credibility of simple "no-gene" mechanisms of assortative mating, in which this trait arises as a pleiotropic effect of genes responsible for ecological adaptation.
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