Evidence map›Paper›PMID 17907147›Full record

Trial reportArthritis and rheumatism2007

Clinical effectiveness of a rehabilitation program integrating exercise, self-management, and active coping strategies for chronic knee pain: a cluster randomized trial.

M V Hurley, N E Walsh, H L Mitchell, T J Pimm, A Patel, E Williamson, R H Jones, P A Dieppe, B C Reeves

2 registry-linked trialsOpen access · bronzeAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Arthritis and rheumatism, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 102 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 17 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03379623 nacompletednot on this mapstarted 2017, after this paper: background citation

A Feasibility Randomised Controlled Trial of the Implementation in Malaysian Healthcare Context of the ESCAPE-pain Programme for Patients With Knee Osteoarthritis

TypeinterventionalSponsorMuhammad Kamil Che HasanRan2017 to 2018Enrolled72ConditionsKnee OsteoarthritisArmsESCAPE-pain Programme
NCT05173064 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Development and Randomized Controlled Trial of an AI-powered Technological Surrogate Physiotherapist (TSP) Dedicated to Quality Enhancement and Cost Reduction in Knee Osteoarthritis Exercise Rehabilitation

TypeinterventionalSponsorThe University of Hong KongRan2026 to 2027Enrolled176ConditionsPain, Knee OsteoarthritisArmsThe AI-powered Technological Surrogate Physiotherapist, Face-to-face physiotherapist-supervised exercise program
3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 17 syntheses or guidelines pooled it, 272 citations in OpenAlex.

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  5. Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2024
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  14. Exercise for osteoarthritis of the knee.The Cochrane database of systematic reviews · 2015
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  15. Self-management education programmes for osteoarthritis.The Cochrane database of systematic reviews · 2014
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42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

M V HurleyKing's College London, London, UK. mike.hurley@kcl.ac.uk
N E Walsh
H L Mitchell
T J Pimm
A Patel
E Williamson
R H Jones
P A Dieppe
B C Reeves
King's College London · GBUniversity of Bristol · GBBuckinghamshire Healthcare NHS Trust · GBDe Montfort University · GBLondon School of Hygiene & Tropical Medicine · GBUniversity of the West of England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveChronic knee pain is a major cause of disability and health care expenditure, but there are concerns about efficacy, cost, and side effects associated with usual primary care. Conservative rehabilitation may offer a safe, effective, affordable alternative. We compared the effectiveness of a rehabilitation program integrating exercise, self-management, and active coping strategies (Enabling Self-management and Coping with Arthritic Knee Pain through Exercise [ESCAPE-knee pain]) with usual primary care in improving functioning in persons with chronic knee pain.

methodsWe conducted a single-blind, pragmatic, cluster randomized controlled trial. Participants age >/=50 years, reporting knee pain for >6 months, were recruited from 54 inner-city primary care practices. Primary care practices were randomized to continued usual primary care (i.e., whatever intervention a participant's primary care physician deemed appropriate), usual primary care plus the rehabilitation program delivered to individual participants, or usual primary care plus the rehabilitation program delivered to groups of 8 participants. The primary outcome was self-reported functioning (Western Ontario and McMaster Universities Osteoarthritis Index physical functioning [WOMAC-func]) 6 months after completing rehabilitation.

resultsA total of 418 participants were recruited; 76 (18%) withdrew, only 5 (1%) due to adverse events. Rehabilitated participants had better functioning than participants continuing usual primary care (-3.33 difference in WOMAC-func score; 95% confidence interval [95% CI] -5.88, -0.78; P = 0.01). Improvements were similar whether participants received individual rehabilitation (-3.53; 95% CI -6.52, -0.55) or group rehabilitation (-3.16; 95% CI -6.55, -0.12).

conclusionESCAPE-knee pain provides a safe, relatively brief intervention for chronic knee pain that is equally effective whether delivered to individuals or groups of participants.

Indexed as

Adaptation, PsychologicalExercise TherapyAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedOsteoarthritis, KneeSelf CareTreatment Outcome

Identifiers

PMID17907147
PMCPMC2673355
OpenAlexW2098653239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.