ReviewBrain research reviews2008
Strategies for delineating spinal locomotor rhythm-generating networks and the possible role of Hb9 interneurones in rhythmogenesis.
Review in Brain research reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
- Lumbar spinal Shox2 interneurons receive monosynaptic excitatory input from the lateral paragigantocellular nucleus in mouse.iScience · 2026Article
- Bidirectional locomotion induces asymmetric limb adaptations.Journal of neurophysiology · 2025Article
- Properties of rhythmogenic currents in spinal Shox2 interneurons across postnatal development.The Journal of physiology · 2025Article
- Forward Stepping Evoked by Transvertebral Stimulation in the Decerebrate Cat.Neuromodulation : journal of the International Neuromodulation Society · 2024Article
- Distinguishing subtypes of spinal locomotor neurons to inform circuit function and dysfunction.Current opinion in neurobiology · 2023Review
- Rare phenomena of central rhythm and pattern generation in a case of complete spinal cord injury.Nature communications · 2023Article
- Identification of adult spinal Shox2 neuronal subpopulations based on unbiased computational clustering of electrophysiological properties.Frontiers in neural circuits · 2022Article
- Control of Mammalian Locomotion by Somatosensory Feedback.Comprehensive Physiology · 2021Article
- Elimination of glutamatergic transmission from Hb9 interneurons does not impact treadmill locomotion.Scientific reports · 2021Article
- Spinal Cord Injury Alters Spinal Shox2 Interneurons by Enhancing Excitatory Synaptic Input and Serotonergic Modulation While Maintaining Intrinsic Properties in Mouse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Simultaneous bidirectional hindlimb locomotion in decerebrate cats.Scientific reports · 2021Article
- Spinal Interneurons as Gatekeepers to Neuroplasticity after Injury or Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Review
- Recent Insights into the Rhythmogenic Core of the Locomotor CPG.International journal of molecular sciences · 2021Review
- The M-current works in tandem with the persistent sodium current to set the speed of locomotion.PLoS biology · 2020Article
- Brainstem neurons that command mammalian locomotor asymmetries.Nature neuroscience · 2020Article
- The rhythm section: An update on spinal interneurons setting the beat for mammalian locomotion.Current opinion in physiology · 2019Article
- Stimulation of Single, Possible CHX10 Hindbrain Neurons Turns Swimming On and Off in YoungFrontiers in cellular neuroscience · 2019Article
- Flexor and Extensor Ankle Afferents Broadly Innervate Locomotor Spinal Shox2 Neurons and Induce Similar Effects in Neonatal Mice.Frontiers in cellular neuroscience · 2019Article
- Mapping Connectivity Amongst Interneuronal Components of the Locomotor CPG.Frontiers in cellular neuroscience · 2019Article
- Article
17 more citing papers are in PubMed but not listed here.
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2 authors.
Funding
Abstract
Despite significant advances in our understanding of pattern generation in invertebrates and lower vertebrates, there have been barriers to the application of the principles learned to the definition of networks underlying mammalian locomotion. Major difficulties have arisen in identifying spinal interneurones in preparations which allow study of neuronal intrinsic properties and the role of identified interneurones in locomotor networks. Recent genetic technologies in which selective expression of fluorescent proteins in specific populations of mouse spinal neurones have provided new avenues of investigation. In this review, we focus on the generation of locomotor rhythm and outline criteria that rhythm-generating neurones might be expected to fulfill. We then examine the extent to which a recently identified population of spinal interneurones, Hb9 interneurones, fulfill these criteria. Finally, we suggest that Hb9 interneurones could be involved in an asymmetric model of locomotor rhythmogenesis through projections of electrotonically coupled rhythm-generating modules to flexor pattern formation half-centres. The principles learned from studying this population of interneurones have led to strategies to systematically evaluate neurones that may be involved in locomotor rhythmogenesis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.