Evidence map›Paper›PMID 17904460›Full record

Trial reportThe American journal of medicine2007

Randomized trial to improve fracture prevention in nursing home residents.

Cathleen S Colón-Emeric, Kenneth W Lyles, Paul House, Deborah A Levine, Anna P Schenck, Jeroan Allison, Joel Gorospe, Mary Fermazin, Kristi Oliver, Jeffrey R Curtis and 3 more

Registry-linked trialOpen access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The American journal of medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00280943 (Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities Written for FDA Approved Medications for Osteoporosis Treatment.), which is not on this map. Cited by 41 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 9 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00280943 phase2 / phase3completednot on this map

Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities Written for FDA Approved Medications for Osteoporosis Treatment.

TypeinterventionalSponsorDuke UniversityRan2005 to 2007Enrolled64ConditionsHip Fractures, OsteoporosisArmsLong-term care facilities in the intervention arm will receive education and feedback audit on performance
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 9 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Audit and feedback: effects on professional practice.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Interventions to improve osteoporosis care: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Pooled it
  3. How Can We Improve Osteoporosis Care? A Systematic Review and Meta-Analysis of the Efficacy of Quality Improvement Strategies for Osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
    Pooled it
  4. Complex interventions can increase osteoporosis investigations and treatment: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Pooled it
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  6. Hip protectors for preventing hip fractures in older people.The Cochrane database of systematic reviews · 2014
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  14. A randomized trial of a mailed intervention and self-scheduling to improve osteoporosis screening in postmenopausal women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2012
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Cathleen S Colón-EmericDuke University Center for Aging and Human Development, Durham, NC 27710, USA. colon001@mc.duke.edu
Kenneth W Lyles
Paul House
Deborah A Levine
Anna P Schenck
Jeroan Allison
Joel Gorospe
Mary Fermazin
Kristi Oliver
Jeffrey R Curtis
Norman Weissman
Aiyuan Xie
Kenneth G Saag
University of Alabama at Birmingham · USThe Carolinas Center · USDuke University · US

Funding

Taste and smell enhancement in older cancer patientsP60AG011268 · NIA · DUKE UNIVERSITY · PI COHEN, HARVEY JAY · 1992 to 2005
$5.8M
Evidence-Based Medicine in the Skilled Nursing FacilityK23AG024787 · NIA · DUKE UNIVERSITY · PI COLON-EMERIC, CATHLEEN S · 2004 to 2008
$815k
UAB CERTs of Musculoskeletal DisordersU18HS010389 · AHRQ · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2000 to 2006
$796k
AHRQ HHS 3U18HS10389-06S1AHRQ HHS U18 HS010389NIA NIH HHS AG-11268NIA NIH HHS K23 AG024787NIA NIH HHS P60 AG011268
6 · The paper itself

Abstract

backgroundInterventions to improve the fracture prevention in nursing homes are needed.

methodsCluster-randomized, single-blind, controlled trial of a multi-modal quality improvement intervention. Nursing homes (n=67) with > or =10 residents with a diagnosis of osteoporosis or recent hip fracture (n=606) were randomized to receive an early or delayed intervention consisting of audit and feedback, educational modules, teleconferences, and academic detailing. Medical record abstraction and the Minimum Data Set were used to measure the prescription of osteoporosis therapies before and after the intervention period. Analysis was at the facility-level and Generalized Estimating Equation modeling was used to account for clustering.

resultsNo significant improvements were observed in any of the quality indicators. The use of osteoporosis pharmacotherapy or hip protectors improved by 8.0% in the intervention group and 0.6% in the control group, but the difference was not statistically significant (P=.72). Participation in the intervention activities was low, but completion of the educational module (odds ratio [OR] 4.8, 95% confidence interval [CI], 1.9-12.0) and direct physician contact by an academic detailer (OR 4.5, 95% CI, 1.1-18.2) were significantly associated with prescription of osteoporosis pharmacotherapy or hip protectors in multivariable models.

conclusionsAudit-feedback and education interventions were ineffective in improving fracture prevention in the nursing home setting, although results may have been tempered by low participation in the intervention activities.

Indexed as

Homes for the AgedNursing HomesAgedAged, 80 and overArizonaFemaleFractures, BoneFractures, SpontaneousHumansMaleMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioOsteoporosisOutcome and Process Assessment, Health Care

Identifiers

PMID17904460
PMCPMC2288656
OpenAlexW2073185768

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.