Evidence map›Paper›PMID 17903623›Full record

ReviewDermatologic clinics2007

Beta adrenergic receptors in keratinocytes.

Raja K Sivamani, Susanne T Lam, R Rivkah Isseroff

Open access · greenAbstract readReview
In one paragraph

Review in Dermatologic clinics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Therapeutic responses toScience translational medicine · 2020
    Trial
  3. Alteration in tissue electrolyte and water balance in pregnant mice: the importance of potassium.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Infantile hemangiomas βPediatric research · 2022
    Article
  11. Article
  12. Article
  13. Cellular benefits of single-use negative pressure wound therapy demonstrated in a novel ex vivo human skin wound model.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2021
    Article
  14. Review
  15. Catecholamines in the regulation of angiogenesis in cutaneous wound healing.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Raja K SivamaniDepartment of Dermatology, University of California, Davis, School of Medicine, Dermatology Research, TB 192, One Shields Avenue, Davis, CA 95616, USA.
Susanne T Lam
R Rivkah Isseroff
University of California, Davis · US

Funding

Supplement: Keratinocyte Galvanotaxis and Wound HealingR01AR044518 · NIAMS · UNIVERSITY OF CALIFORNIA DAVIS · PI ISSEROFF, ROSLYN R · 1998 to 2006
$2.5M
NIAMS NIH HHS R01 AR044518
6 · The paper itself

Abstract

Beta2 adrenergic receptors were identified in keratinocytes more than 30 years ago, but their function in the epidermis continues to be elucidated. Abnormalities in their expression, signaling pathway, or in the generation of endogenous catecholamine agonists by keratinocytes have been implicated in the pathogenesis of cutaneous diseases such as atopic dermatitis, vitiligo, and psoriasis. New studies also indicate that the beta2AR also modulates keratinocyte migration, and thus can function to regulate wound reepithelialization. This review focuses on the function of these receptors in keratinocytes and their contribution to cutaneous physiology and disease.

Indexed as

CatecholaminesCell MovementCyclic AMPDermatitis, AtopicHumansIntracellular Signaling Peptides and ProteinsKeratinocytesPsoriasisReceptors, Adrenergic, beta-2Signal TransductionSkin DiseasesVitiligoWound HealingCatecholaminesCyclic AMPIntracellular Signaling Peptides and ProteinsReceptors, Adrenergic, beta-2

Identifiers

PMID17903623
PMCPMC2169297
OpenAlexW2152457676

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.