ArticleEuropean child & adolescent psychiatry2007
The Maudsley early onset schizophrenia study. Predictors of psychosocial outcome at 4-year follow-up.
Article in European child & adolescent psychiatry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Predictors of long-term outcome of patients with schizophrenia in Africa: systematic review and meta-analysis.BMC public health · 2025Pooled it
- Knowledge domain and trends in treatment-resistant schizophrenia (TRS) research based on CiteSpace bibliometrics analysis.Frontiers in pharmacology · 2024Pooled it
- Pooled it
- A systematic review of the long-term outcome of early onset schizophrenia.BMC psychiatry · 2012Pooled it
- The mesolimbic system and the loss of higher order network features in schizophrenia when learning without reward.Frontiers in psychiatry · 2024Article
- Lost in Translation: Challenges in the Diagnosis and Treatment of Early-Onset Schizophrenia.Cureus · 2023Review
- Evidence of discontinuity between psychosis-risk and non-clinical samples in the neuroanatomical correlates of social function.Schizophrenia research. Cognition · 2022Article
- Maintenance electroconvulsive therapy: Are we clutching at straws?Journal of family medicine and primary care · 2022Article
- Whole Life: a feasibility study of a recovery-focussed intervention in patients with stabilised schizophrenia.NIHR open research · 2021Article
- Long-Term Outcomes and Predictors of Childhood-Onset Schizophrenia: A Naturalistic Study of 6-year Follow-Up in China.Frontiers in psychiatry · 2021Article
- Early and very early-onset schizophrenia compared with adult-onset schizophrenia: French FACE-SZ database.Brain and behavior · 2020Article
- Social skills, executive functioning and social engagement.Schizophrenia research. Cognition · 2019Article
- Negative Symptoms in Early-Onset Psychosis and Their Association With Antipsychotic Treatment Failure.Schizophrenia bulletin · 2019Article
- A Review of Childhood-Onset Schizophrenia.Focus (American Psychiatric Publishing) · 2016Article
- Strong family history and early onset of schizophrenia: about 2 families in Northern Nigeria.The Pan African medical journal · 2016Article
- The Effect of Paternal Age on Relapse in First-Episode Schizophrenia.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2015Article
- Predictors of outcome in early-onset psychosis: a systematic review.NPJ schizophrenia · 2015Review
- Brain network informed subject community detection in early-onset schizophrenia.Scientific reports · 2014Article
- Association of a Serotonin Receptor 2A Gene Polymorphism with Visual Sustained Attention in Early-Onset Schizophrenia Patients and their Non-Psychotic Siblings.Aging and disease · 2012Article
- Processing speed and executive functions predict real-world everyday living skills in adolescents with early-onset schizophrenia.European child & adolescent psychiatry · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the contribution of premorbid function, duration of untreated psychosis (DUP), age of onset, severity of symptoms at presentation, and number of subsequent hospitalisations to the outcome of early onset schizophrenia (EOS; onset before 17th birthday).
methodTwenty-three EOS patients (mean age at onset 15.16 +/- 1.39 years) were re-assessed after a mean interval of 4 +/- 1.08 years. At baseline and follow-up clinical diagnoses were confirmed using the Structured Clinical Interview for DSM-IV Axis I Disorders and symptoms were assessed with the Positive and Negative Syndrome Scale. Premorbid function, as measured with the Premorbid Adjustment Scale, age of onset and DUP were assessed at baseline only. Outcome was evaluated using the Social Adaptation Self-Evaluation Scale (SASS) and the Global Assessment of Functioning (GAF) Scale.
resultsMean DUP was 2.95 +/- 3.59 months and mean total PAS score was 6.65 +/- 3.02. They had an average of 2.09 +/- 1.44 hospitalisations and their mean SASS and GAF scores were 37.27 +/- 6.5 and 54.19 +/- 18.99, respectively. Poor childhood premorbid function and the severity of negative symptoms at baseline were correlated with worse SASS and GAF scores. No other significant associations were found.
conclusionsPoor childhood function is the most significant predictor of outcome in EOS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.