ArticleJournal of molecular evolution2007
Borrelia lusitaniae OspA gene heterogeneity in Mediterranean basin area.
Article in Journal of molecular evolution, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Comparative genomics of Borrelia lusitaniae.G3 (Bethesda, Md.) · 2026Article
- Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024Review
- Development of a sequence-basedMicrobial genomics · 2024Article
- Evolutionary dynamics and geographical dispersal ofFrontiers in microbiology · 2024Article
- Investigation of Tick-Borne Pathogens inPathogens (Basel, Switzerland) · 2021Article
- The Population Structure ofMicroorganisms · 2021Article
- Lyme borreliosis, Po River Valley, Italy.Emerging infectious diseases · 2010Article
- Vasculitis-like syndrome associated with Borrelia lusitaniae infection.Clinical rheumatology · 2008Article
- Fine-scale phylogeographic structure of Borrelia lusitaniae revealed by multilocus sequence typing.PloS one · 2008Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, Borrelia lusitaniae DNA extracted from ticks and lizards was used to amplify the outer surface protein A (OspA) gene in order to increase knowledge about sequence variability in the Mediterranean basin area, to better understand how Borrelia lusitaniae has evolved and how its distribution has expanded. Phylogenetic trees including Italian and reference sequences showed a clear separation of B. lusitaniae OspA strains in two different major clades. North African isolates form a clade with Portuguese POTIB strains, whereas Italian samples are grouped with German strains and a human Portuguese strain. This subdivision was supported by very high posterior probability values in the trees, by both analysis of molecular variance and selective pressure. These results, based on phylogenetic information contained in the OspA gene sequences, show the presence of two different B. lusitaniae strains circulating in the Mediterranean basin area, suggesting two different evolution paths.
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Registered trials
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