ArticlePhysiological genomics2007
Differences in postingestive metabolism of glutamate and glycine between C57BL/6ByJ and 129P3/J mice.
Article in Physiological genomics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Glutamate can act as a signaling molecule in mouse preimplantation embryos†.Biology of reproduction · 2022Article
- The Protective Effect of Anthocyanins Extracted fromMediators of inflammation · 2021Article
- Expanding the Functional Scope of the Fmoc-Diphenylalanine Hydrogelator by Introducing a Rigidifying and Chemically Active Urea Backbone Modification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019Article
- Empagliflozin, SGLTNaunyn-Schmiedeberg's archives of pharmacology · 2018Article
- Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- Flavor Preferences Conditioned by Dietary Glutamate.Advances in nutrition (Bethesda, Md.) · 2016Review
- Genetics of Amino Acid Taste and Appetite.Advances in nutrition (Bethesda, Md.) · 2016Review
- Dietary proteins and food-related reward signals.Food & nutrition research · 2011Article
- Nutrient selection in the absence of taste receptor signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Taste perception of monosodium glutamate and inosine monophosphate by 129P3/J and C57BL/6ByJ mice.Physiology & behavior · 2009Article
- Glutamate taste and appetite in laboratory mice: physiologic and genetic analyses.The American journal of clinical nutrition · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Amino acids are essential nutrients for living organisms. There are genetic differences in voluntary consumption of amino acids among mouse strains. In two-bottle preference tests, C57BL/6ByJ (B6) mice consume more glutamate (Glu) and glycine (Gly) solutions than do 129P3/J (129) mice. To examine the role of postingestive metabolism of these amino acids in regulation of their intake, we compared metabolism of orally administered Glu and Gly in B6 and 129 mice. After administration of Glu, there were increases in circulating glucose and insulin in B6 mice, whereas 129 mice had elevated blood alanine and body temperature. After ingestion of Gly, B6 mice had increases in blood glucose, whereas there was an elevation of body temperature in 129 mice. These data suggest that B6 mice preferentially convert ingested Glu and Gly to glucose in contrast to 129 mice, which preferentially use them for thermogenesis. This study strongly supports the hypothesis that the metabolic fate of a nutrient plays an important regulatory role in control of its intake. This is the first detailed study of mouse strain differences in amino acid metabolism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.