ReviewJournal of molecular medicine (Berlin, Germany)2007
Emerging role of dendritic cells in respiratory viral infection.
Review in Journal of molecular medicine (Berlin, Germany), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Postinfectious Pulmonary Complications: Establishing Research Priorities to Advance the Field: An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2024Review
- Airway cholinergic history modifies mucus secretion properties to subsequent cholinergic challenge in diminished chloride and bicarbonate conditions.Experimental physiology · 2020Article
- Influenza virus N-linked glycosylation and innate immunity.Bioscience reports · 2019Review
- Intranasal administration of poly-gamma glutamate induced antiviral activity and protective immune responses against H1N1 influenza A virus infection.Virology journal · 2015Article
- Human metapneumovirus keeps dendritic cells from priming antigen-specific naive T cells.Immunology · 2013Article
- Review
- Protein energy malnutrition decreases immunity and increases susceptibility to influenza infection in mice.The Journal of infectious diseases · 2013Article
- Critical role of MDA5 in the interferon response induced by human metapneumovirus infection in dendritic cells and in vivo.Journal of virology · 2013Article
- Rapid differentiation of monocytes into type I IFN-producing myeloid dendritic cells as an antiviral strategy against influenza virus infection.Journal of immunology (Baltimore, Md. : 1950) · 2012Article
- Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success.Journal of thoracic disease · 2012Article
- Epithelial cells, the "switchboard" of respiratory immune defense responses: effects of air pollutants.Swiss medical weekly · 2012Review
- Major histocompatibility complex class II expression and hemagglutinin subtype influence the infectivity of type A influenza virus for respiratory dendritic cells.Journal of virology · 2011Article
- ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia.PLoS pathogens · 2011Article
- Epithelial cells from smokers modify dendritic cell responses in the context of influenza infection.American journal of respiratory cell and molecular biology · 2011Article
- Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function.BMC infectious diseases · 2011Article
- The human metapneumovirus matrix protein stimulates the inflammatory immune response in vitro.PloS one · 2011Article
- Primary human mDC1, mDC2, and pDC dendritic cells are differentially infected and activated by respiratory syncytial virus.PloS one · 2011Article
- The airway epithelium: soldier in the fight against respiratory viruses.Clinical microbiology reviews · 2011Review
- Characterization of intestinal dendritic cells in murine norovirus infection.The open immunology journal · 2011Article
- Aryl hydrocarbon receptor activation reduces dendritic cell function during influenza virus infection.Toxicological sciences : an official journal of the Society of Toxicology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory viral infections are a major health problem, especially in the immunocompromised, young, and elderly. In order for the host to effectively clear viral infections, a productive adaptive immune response must be developed. Crucial to the initiation of the adaptive response is the dendritic cell, which induces the proliferation and activation of T cells early in an antiviral response. This review examines the role of lung dendritic cells in the immune response to respiratory viruses. The phenotypic and functional differences between conventional and plasmacytoid dendritic cells are discussed, as are the mechanisms behind homeostatic recruitment of these cells in the normal lung. Focusing on respiratory syncytial virus and influenza, the role of the two dendritic cell subsets during an antiviral response is explored. Through evolution, viruses have developed several mechanisms to interfere with the normal function of dendritic cells and prevent appropriate induction of an adaptive immune response, which are also discussed. Finally, we identify potential targets for future therapeutic strategies to ameliorate disease caused by respiratory virus infection.
Indexed as
Identifiers
17891367What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.