Evidence map›Paper›PMID 17890365›Full record

ArticleGenetics2007

Bedraggled, a putative transporter, influences the tissue polarity complex during the R3/R4 fate decision in the Drosophila eye.

Amy S Rawls, Sarah A Schultz, Robi D Mitra, Tanya Wolff

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Planar cell polarity signaling in the Drosophila eye.Current topics in developmental biology · 2010
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amy S RawlsDepartment of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Sarah A Schultz
Robi D Mitra
Tanya Wolff
Washington University in St. Louis · US

Funding

ESTABLISHMENT OF POLARITY IN RETINAL DEVELOPMENTR01EY013136 · NEI · WASHINGTON UNIVERSITY · PI WOLFF, TANYA · 2000 to 2003
$1.2M
NEI NIH HHS EY13136NEI NIH HHS R01 EY013136
6 · The paper itself

Abstract

The tissue polarity pathway is required for the establishment of epithelial polarity in a variety of vertebrate and invertebrate organs. Core tissue polarity proteins act in a dynamically regulated complex to direct the polarization of the Drosophila eye. We report the identification and characterization of bedraggled (bdg), a novel gene that regulates one output of the tissue polarity pathway--the establishment of the R3/R4 photoreceptor fates. bdg encodes a novel, putative transporter protein and interacts genetically with all of the core polarity genes to influence the specification of the R3 and R4 cell fates. Finally, bdg is required for both viability and the initial stages of imaginal disc development.

Indexed as

Cell PolarityAnimalsAnimals, Genetically ModifiedBlotting, NorthernCell DifferentiationCell LineageDrosophila melanogasterDrosophila ProteinsEyeFemaleGene Expression Regulation, DevelopmentalIn Situ HybridizationMaleMotor ActivityPhenotypePhylogenyDrosophila Proteins

Identifiers

PMID17890365
PMCPMC2013731
OpenAlexW2006424898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.