ArticleNucleic acids research2008
MethyCancer: the database of human DNA methylation and cancer.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
73 citing papers in PubMed, 144 citations in OpenAlex.
- TiSMeD: A tissue-specific methylation and expression database for biomarker and translational applications.Molecular therapy. Nucleic acids · 2026Article
- Computational models for pan-cancer classification based on multi-omics data.Frontiers in genetics · 2025Review
- CancerMHL: the database of integrating key DNA methylation, histone modifications and lncRNAs in cancer.Database : the journal of biological databases and curation · 2024Article
- Biomedical Big Data Technologies, Applications, and Challenges for Precision Medicine: A Review.Global challenges (Hoboken, NJ) · 2024Review
- CanMethdb: a database for genome-wide DNA methylation annotation in cancers.Bioinformatics (Oxford, England) · 2023Article
- Expanding adverse outcome pathways towards one health models for nanosafety.Frontiers in toxicology · 2023Article
- Prostate cancer in omics era.Cancer cell international · 2022Article
- ImmuMethy, a database of DNA methylation plasticity at a single cytosine resolution in human blood and immune cells.Database : the journal of biological databases and curation · 2022Article
- Progressing Towards a Human-Centric Approach in Cancer Research.Frontiers in oncology · 2022Review
- Pan-Cancer Analysis Predicts FOXS1 as a Key Target in Prognosis and Tumor Immunotherapy.International journal of general medicine · 2022Article
- dbGENVOC: database of GENomic Variants of Oral Cancer, with special reference to India.Database : the journal of biological databases and curation · 2021Article
- Computational methods and next-generation sequencing approaches to analyze epigenetics data: Profiling of methods and applications.Methods (San Diego, Calif.) · 2021Review
- MethHC 2.0: information repository of DNA methylation and gene expression in human cancer.Nucleic acids research · 2021Article
- Whole-genome bisulfite sequencing of abdominal adipose reveals DNA methylation pattern variations in broiler lines divergently selected for fatness.Journal of animal science · 2021Article
- Systems Biology and Experimental Model Systems of Cancer.Journal of personalized medicine · 2020Review
- Regulatory Mechanisms of Epigenetic miRNA Relationships in Human Cancer and Potential as Therapeutic Targets.Cancers · 2020Review
- methCancer-gen: a DNA methylome dataset generator for user-specified cancer type based on conditional variational autoencoder.BMC bioinformatics · 2020Article
- Construction of an integrated human osteosarcoma database, HOsDb, based on literature mining, microarray analysis, and database retrieval.BMC cancer · 2020Article
- EWAS Data Hub: a resource of DNA methylation array data and metadata.Nucleic acids research · 2020Article
- Artificial Intelligence to Decode Cancer Mechanism: Beyond Patient Stratification for Precision Oncology.Frontiers in pharmacology · 2020Review
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cancer is ranked as one of the top killers in all human diseases and continues to have a devastating effect on the population around the globe. Current research efforts are aiming to accelerate our understanding of the molecular basis of cancer and develop effective means for cancer diagnostics, treatment and prognosis. An altered pattern of epigenetic modifications, most importantly DNA methylation events, plays a critical role in tumorigenesis through regulating oncogene activation, tumor suppressor gene silencing and chromosomal instability. To study interplay of DNA methylation, gene expression and cancer, we developed a publicly accessible database for human DNA Methylation and Cancer (MethyCancer, http://methycancer.genomics.org.cn). MethyCancer hosts both highly integrated data of DNA methylation, cancer-related gene, mutation and cancer information from public resources, and the CpG Island (CGI) clones derived from our large-scale sequencing. Interconnections between different data types were analyzed and presented. Furthermore, a powerful search tool is developed to provide user-friendly access to all the data and data connections. A graphical MethyView shows DNA methylation in context of genomics and genetics data facilitating the research in cancer to understand genetic and epigenetic mechanisms that make dramatic changes in gene expression of tumor cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.