Evidence map›Paper›PMID 17889314›Full record

Trial reportAlcohol (Fayetteville, N.Y.)2007

Bupropion and nicotine patch as smoking cessation aids in alcoholics.

Kathleen M Grant, Stephanie Sinclair Kelley, Lynette M Smith, Sangeeta Agrawal, James R Meyer, Debra J Romberger

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Alcohol (Fayetteville, N.Y.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Guideline
  2. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Pooled it
  4. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2014
    Pooled it
  5. Guideline
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Antidepressants for smoking cessation.The Cochrane database of systematic reviews · 2023
    Review
  12. Article
  13. Smoking As an Outcome Moderator In the Treatment of Alcohol Use Disorders.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Treatment of tobacco dependence in mental health and addictive disorders.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kathleen M GrantSubstance Use Disorders Program, 116A4, Veterans Administration Nebraska Western Iowa Health Care System (Omaha site), 4101 Woolworth Avenue, Omaha, NE 68105, USA. Kathleen.grant2@med.va.gov
Stephanie Sinclair Kelley
Lynette M Smith
Sangeeta Agrawal
James R Meyer
Debra J Romberger
University of Nebraska Medical Center · USVA Nebraska Western Iowa Health Care System · US

Funding

Bupropion as a Smoking Cessation Aid in AlcoholicsR21AA013689 · NIAAA · OMAHA VA MEDICAL CENTER · PI GRANT, KATHLEEN MARY · 2002 to 2003
$150k
NIAAA NIH HHS R21 AA013689NIAAA NIH HHS R21 AA13689-01
6 · The paper itself

Abstract

This is a double-blind placebo-controlled study of sustained-release bupropion as a smoking cessation aid in alcoholics undergoing treatment for their alcoholism. Participants (N=58) were enrolled within 1 week of entry into alcohol treatment from community and Veterans Affairs Substance Use Disorder programs. All participants received nicotine patch and were invited to attend a smoking cessation lecture and group. Cigarette smoking and alcohol outcomes were measured at 6 months. Bupropion when added to nicotine patch did not improve smoking outcomes. One third of participants on bupropion reported discontinuing the drug during weeks 1-4. Participants reported cigarette outcomes with nicotine patch that are similar to those seen in the general population. All study participants significantly reduced cigarette use. Comorbid affective disorder or antipersonality disorder did not affect outcomes. Alcohol outcomes were improved in those who discontinued cigarettes.

Indexed as

Smoking PreventionAdministration, CutaneousAdultAlcoholismBupropionCommunity Health ServicesDelayed-Action PreparationsDouble-Blind MethodFemaleHumansMaleMiddle AgedNebraskaNeurotransmitter Uptake InhibitorsNicotineNicotinic AgonistsBupropionDelayed-Action PreparationsNeurotransmitter Uptake InhibitorsNicotineNicotinic Agonists

Identifiers

PMID17889314
PMCPMC2064868
OpenAlexW2045003547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.