ArticleBMC evolutionary biology2007
Environmental variability and modularity of bacterial metabolic networks.
Article in BMC evolutionary biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.
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Who cites it
98 citing papers in PubMed, 206 citations in OpenAlex.
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- Microbial biotechnology meets ecological theory: a unified framework to design industrial microbial consortia.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Review
- microbetag: simplifying microbial network interpretation through annotation, enrichment tests, and metabolic complementarity analysis.Genome biology · 2025Article
- The Reverse Ecology-Based Approach to Design a Bacterial Consortium as Soybean Bioinoculant.Current microbiology · 2024Article
- Metabolites of pathogenic microorganisms database (MPMdb) and its seed metabolite applications.Microbiology spectrum · 2024Article
- Microbial metabolism influences microplastic perturbation of dissolved organic matter in agricultural soils.The ISME journal · 2024Article
- Comparative genome analyses of clinical and non-clinicalFrontiers in microbiology · 2024Article
- Having multiple selves helps learning agents explore and adapt in complex changing worlds.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Functional comparison of metabolic networks across species.Nature communications · 2023Article
- BioNAR: an integrated biological network analysis package in bioconductor.Bioinformatics advances · 2023Article
- Trait-trait relationships and tradeoffs vary with genome size in prokaryotes.Frontiers in microbiology · 2022Article
- Climatic Alterations Influence Bacterial Growth, Biofilm Production and Antimicrobial Resistance Profiles inAntibiotics (Basel, Switzerland) · 2021Article
- Rapid evolution of trait correlation networks during bacterial adaptation to the rhizosphere.Evolution; international journal of organic evolution · 2021Article
- Effect of Temperature on Heart Rate forInsects · 2021Article
- Modularity in Biological Networks.Frontiers in genetics · 2021Review
- Bacterial Communities Present Distinct Co-occurrence Networks in Sediment and Water of the Thermokarst Lakes in the Yellow River Source Area.Frontiers in microbiology · 2021Article
- Construction, comparison and evolution of networks in life sciences and other disciplines.Journal of the Royal Society, Interface · 2020Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiological systems are often modular: they can be decomposed into nearly-independent structural units that perform specific functions. The evolutionary origin of modularity is a subject of much current interest. Recent theory suggests that modularity can be enhanced when the environment changes over time. However, this theory has not yet been tested using biological data.
resultsTo address this, we studied the relation between environmental variability and modularity in a natural and well-studied system, the metabolic networks of bacteria. We classified 117 bacterial species according to the degree of variability in their natural habitat. We find that metabolic networks of organisms in variable environments are significantly more modular than networks of organisms that evolved under more constant conditions.
conclusionThis study supports the view that variability in the natural habitat of an organism promotes modularity in its metabolic network and perhaps in other biological systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.