Evidence map›Paper›PMID 17885295›Full record

ArticleAIDS (London, England)2007

Prevalence and factors associated with dry skin in HIV infection: the FRAM study.

Daniel Lee, Constance A Benson, Cora E Lewis, Carl Grunfeld, Rebecca Scherzer

Open access · greenAbstract read
In one paragraph

Article in AIDS (London, England), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Contamination of pulse oximeter probes before and after decontamination in two intensive care units.The Southern African journal of critical care : the official journal of the Critical Care Society · 2019
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Daniel LeeDepartment of Medicine, University of California-San Diego, CA, USA.
Constance A Benson
Cora E Lewis
Carl Grunfeld
Rebecca Scherzer
University of California, San Diego · USUniversity of Alabama at Birmingham · USUniversity of California, San Francisco · US

Funding

ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI KOSMISKI, LISA A. · 1985 to 2008
$52.6M
ZDV &3TC NEVIRAPINE COMBINATION THERAPY IN HIV 1 INFECTED INFANTS &M01RR000865 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WASHINGTON, ARNOLD E. · 1985 to 2011
$43.4M
ZINC AND CA EDTA THERAPY OF PLUMBISMM01RR000052 · NCRR · JOHNS HOPKINS UNIVERSITY · PI BELCHER, HAROLYN MILLICENT EDITH · 1985 to 2007
$37.3M
YOGA FOR THE MANAGEMENT OF HIV-METABOLIC SYNDROMESM01RR000036 · NCRR · WASHINGTON UNIVERSITY · PI NEWCOMER, JOHN W. · 1985 to 2007
$25.4M
WELFARE REFORM AND THE PERINATAL HEALTH OF IMMIGRANTSM01RR000083 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KESSLER, DAVID A · 1985 to 2006
$21.1M
ZIDOVUDINE &LAMIVUDINE ALONE OR IN COMBINATION ON BODY COMPOSITIONM01RR000054 · NCRR · TUFTS MEDICAL CENTER · PI RAO, MADHUMATHI · 1985 to 2005
$12.2M
Fat Redistribution and Metabolic Change in HIV InfectionR01HL074814 · NHLBI · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI GRUNFELD, CARL · 2003 to 2006
$11.0M
FAT REDISTRIBUTION AND METABOLIC CHANGE IN HIV INFECTIONR01DK057508 · NIDDK · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI GRUNFELD, CARL · 1999 to 2002
$5.8M
VISCERAL FAT, METABOLIC RATE AND CVD IN YOUNG ADULTSR01HL053359 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI SIDNEY, STEPHEN · 1995 to 2002
$1.5M
NCRR NIH HHS M01 RR000036NCRR NIH HHS M01 RR000051NCRR NIH HHS M01 RR000052NCRR NIH HHS M01 RR000054NCRR NIH HHS M01 RR000083NCRR NIH HHS M01 RR 00036NCRR NIH HHS M01 RR000865NCRR NIH HHS RR 00051NCRR NIH HHS RR 00052NCRR NIH HHS RR 00054NCRR NIH HHS RR 00083NCRR NIH HHS RR 00865NCRR NIH HHS RR 0636NHLBI NIH HHS HL 53359NHLBI NIH HHS HL 74814NHLBI NIH HHS R01 HL074814NIDDK NIH HHS R01 DK057508NIDDK NIH HHS R01 DK 57508
6 · The paper itself

Abstract

objectiveComplaints of dry skin in HIV-infected individuals were reported after the advent of HAART. The objective of the study was to evaluate the prevalence of dry skin and associated factors in HIV-infected and control subjects.

designCross-sectional.

methodsA total of 1026 HIV-infected subjects and 274 controls [from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a population-based study of cardiovascular risk assessment] in the Study of Fat Redistribution and Metabolic Change in HIV infection (FRAM) had skin assessed by self-report and examination. Multivariable logistic regression identified factors associated with dry skin.

resultsSelf-reported dry skin was more prevalent in HIV-infected subjects than controls. In multivariable analysis, HIV infection was associated with self-reported dry skin. In HIV-infected men, current indinavir use, CD4 cell count less than 200 cells/microl and recent opportunistic infections were associated with dry skin. Indinavir use had an elevated risk in men with CD4 cell counts of 200 cells/microl or greater but not with CD4 cell counts less than 200 cells/microl. In HIV-infected women, a CD4 cell count less than 200 cells/microl was associated with dry skin; indinavir use did not reach statistical significance but, as in men, indinavir use had an elevated risk in those with higher CD4 cell counts than in those with CD4 cell counts less than cells/microl.

conclusionDry skin is more common in HIV-infected individuals than controls. In HIV-infected individuals, low CD4 cell counts and indinavir use in those with higher CD4 cell counts are associated with dry skin.

Indexed as

AdultAntiretroviral Therapy, Highly ActiveCase-Control StudiesCD4 Lymphocyte CountCross-Sectional StudiesFemaleHIV InfectionsHIV Protease InhibitorsHumansIndinavirMaleMiddle AgedPrevalenceRisk FactorsSkin DiseasesUnited StatesHIV Protease InhibitorsIndinavir

Identifiers

PMID17885295
PMCPMC3166536
OpenAlexW2061578680

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.