Evidence map›Paper›PMID 17885193›Full record

ArticleRadiology2007

Metabolic imaging of myocardial triglyceride content: reproducibility of 1H MR spectroscopy with respiratory navigator gating in volunteers.

Rutger W van der Meer, Joost Doornbos, Sebastian Kozerke, Michael Schär, Jeroen J Bax, Sebastiaan Hammer, Johannes W A Smit, Johannes A Romijn, Michaela Diamant, Luuk J Rijzewijk and 2 more

2 registry-linked trialsAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Radiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01761318 phase4completedstarted 2013, after this paper: background citation

Magnetic Resonance Assessment of Victoza Efficacy in the Regression of Cardiovascular Dysfunction In Type 2 Diabetes Mellitus

Ran2013Enrolled50Registered outcomes48Posted comparisons0ConditionsCardiovascular Disease, Diabetes Mellitus Type 2, Diastolic Dysfunction, Fatty LiverArmsliraglutide, Liraglutide - Placebo
Open the trial in the graph
NCT02663362 recruitingnot on this mapstarted 2012, after this paper: background citation

Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications

TypeobservationalSponsorAdventHealth Translational Research InstituteRan2012 to 2027Enrolled250ConditionsHuman Body Composition, Human Body FunctionArmsTo evaluate the reproducibility of acquiring multi-nuclear data on a new 3T Philips Magnet
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 121 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Ectopic Fat Accumulation in Pancreas and Heart.Journal of clinical medicine · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Non-Water-SuppressedScientific reports · 2017 · on this map
    Article
  13. La Radiologia medica · 2017
    Article
  14. Myocardial lipid content in Fabry disease: a combinedBMC cardiovascular disorders · 2016
    Article
  15. Review
  16. The Flexibility of Ectopic Lipids.International journal of molecular sciences · 2016
    Review
  17. Article
  18. Lipid Use and Misuse by the Heart.Circulation research · 2016
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Rutger W van der MeerDepartment of Radiology, Leiden University Medical Center, Albinusdreef 2, C2-S, 2333 ZA Leiden, the Netherlands.
Joost Doornbos
Sebastian Kozerke
Michael Schär
Jeroen J Bax
Sebastiaan Hammer
Johannes W A Smit
Johannes A Romijn
Michaela Diamant
Luuk J Rijzewijk
Albert de Roos
Hildo J Lamb
Leiden University Medical Center · NLLeiden University · NLNovem (Netherlands) · NLInstitute for Biomedical Engineering · CHPhilips (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Institutional review board approval and informed consent were obtained. The purpose of the study was to prospectively compare spectral resolution and reproducibility of hydrogen 1 (1H) magnetic resonance (MR) spectroscopy, with and without respiratory motion compensation based on navigator echoes, in the assessment of myocardial triglyceride content in the human heart. In 20 volunteers (14 men, six women; mean age+/-standard error, 31 years+/-2.8 [range, 19-60 years]; body mass index, 19-30 kg/m2) without history of cardiovascular disease, 1H MR spectroscopy of the myocardium was performed at rest, with and without respiratory motion compensation. Unsuppressed water signal linewidth changed from 11.9 Hz to 10.7 Hz (P<.001) with the use of the navigator, which indicated better spectral resolution. The navigator improved the intraclass correlation coefficient for the assessment of myocardial triglyceride content from 0.32 to 0.81. Therefore, the authors believe that respiratory motion correction is essential for reproducible assessment of myocardial triglycerides.

Indexed as

RespirationAdultFemaleHumansMagnetic Resonance SpectroscopyMaleMiddle AgedMotionMyocardiumProspective StudiesReproducibility of ResultsTriglyceridesTriglycerides

Identifiers

PMID17885193
OpenAlexW2100097749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.