ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2007
Noninvasive assessment of the effects of glucagon on the gastric slow wave.
Article in American journal of physiology. Gastrointestinal and liver physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Multichannel magnetogastrogram: a clinical marker for pediatric chronic nausea.American journal of physiology. Gastrointestinal and liver physiology · 2022Article
- Magnetoenterography for the Detection of Partial Mesenteric Ischemia.The Journal of surgical research · 2019Article
- Noninvasive Magnetogastrography Detects Erythromycin-Induced Effects on the Gastric Slow Wave.IEEE transactions on bio-medical engineering · 2019Article
- Progress in Mathematical Modeling of Gastrointestinal Slow Wave Abnormalities.Frontiers in physiology · 2017Review
- Simultaneous anterior and posterior serosal mapping of gastric slow-wave dysrhythmias induced by vasopressin.Experimental physiology · 2016Article
- Variations in blood glucose levels following gastrostomy tube insertion in a paediatric population.Pediatric radiology · 2014Observational
- Noninvasive biomagnetic detection of isolated ischemic bowel segments.IEEE transactions on bio-medical engineering · 2013Article
- Biomagnetic and bioelectric detection of gastric slow wave activity in normal human subjects--a correlation study.Physiological measurement · 2012Article
- Influence of body parameters on gastric bioelectric and biomagnetic fields in a realistic volume conductor.Physiological measurement · 2012Article
- Effects of volume conductor and source configuration on simulated magnetogastrograms.Physics in medicine and biology · 2010Article
- Biomagnetic signatures of uncoupled gastric musculature.Neurogastroenterology and motility · 2009Article
- The virtual intestine: in silico modeling of small intestinal electrophysiology and motility and the applications.Wiley interdisciplinary reviews. Systems biology and medicineReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Hyperglycemic effects on the gastric slow wave are not well understood, and no studies have examined the effects that hyperglycemia has on gastric slow wave magnetic fields. We recorded multichannel magnetogastrograms (MGGs) before and after intravenous administration of glucagon and subsequent modest hyperglycemia in 20 normal volunteers. Normal slow waves were evident in baseline MGG recordings from all 20 subjects, but within 15 min after glucagon had been given, we noted significant effects on MGG signals. In addition to an overall decrease in the slow wave frequency from 2.9 +/- 0.5 cycles per min (cpm) to 2.2 +/- 0.1 cpm (P < 0.05), we observed significant changes in the number and range of spectral peaks recorded. Furthermore, the propagation velocity determined from surface current density maps computed from the multichannel MGG decreased significantly (7.1 +/- 0.8 mm/s to 5.0 +/- 0.3 mm/s, P < 0.05). This is the first study of biomagnetic effects of hyperglycemia in normal subjects. Our results suggest that the analysis of the MGG provides parameter quantification for gastric electrical activity specific to and characteristic of slow wave abnormalities associated with increased serum glucose by injection of glucagon.
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Registered trials
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