Evidence map›Paper›PMID 17882508›Full record

ArticleCurrent microbiology2007

Impact of anatomic site on growth, efflux-pump expression, cell structure, and stress responsiveness of Bacteroides fragilis.

Lilian Pumbwe, Christopher A Skilbeck, Hannah M Wexler

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Biofilms and Benign Colonic Diseases.International journal of molecular sciences · 2022
    Review
  2. Marine drugs · 2021
    Article
  3. Article
  4. Review
  5. Bacteroides: the good, the bad, and the nitty-gritty.Clinical microbiology reviews · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lilian PumbweGreater Los Angeles Veterans Administration Healthcare Systems, University of California, Los Angeles, CA, USA. lilskil@ucla.edu
Christopher A Skilbeck
Hannah M Wexler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated whether B. fragilis from various human sites acquired stable traits enabling it to express certain efflux pumps (EPs), adopt a particular cell structure, and tolerate certain stressors. Isolates from blood, abscess, and stool (n = 11 each) were investigated. Bacteria from various sites portrayed different ultrastructres and EP expression. Blood isolates were tolerant to nutrient limitation and stool isolates to NaCl and bile salt stress. Stressors significantly increased EP expression. These data demonstrate that (1) B. fragilis acquires stable traits from various in vivo microenvironments; (2) that EPs are involved in stress responsiveness; and (3) that EP expression is tightly controlled and site dependent.

Indexed as

AbscessBacterial ProteinsBacteroides fragilisBacteroides InfectionsGene Expression Regulation, BacterialHumansMembrane Transport ProteinsMicroscopy, Electron, TransmissionBacterial ProteinsMembrane Transport Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.