Evidence map›Paper›PMID 17882381›Full record

ArticleJournal of computer-aided molecular design2007

IA, database of known ligands of aminoacyl-tRNA synthetases.

Mieczyslaw Torchala, Marcin Hoffmann

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of computer-aided molecular design, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mieczyslaw TorchalaBioInfoBank Institute, ul. Limanowskiego 24A, Poznan, 60-744, Poland.
Marcin Hoffmann
BioInfoBank Institute · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The IA database contains 240 structures of known inhibitors of aminoacyl-tRNA synthetases. Structures can be downloaded in different file formats (mol, sdf, smile, png). The search engine offers possibility of searching for the ligands with a given functional group. Additionally, one can search for ligands that act on selected synthetases and from particular references. The data include information which synthetase a given ligand inhibits together with the inhibition constant (IC50) if known.

Indexed as

Databases, FactualRNA, TransferAmino Acyl-tRNA SynthetasesBinding SitesKineticsStructure-Activity RelationshipAmino Acyl-tRNA SynthetasesRNA, Transfer

Identifiers

PMID17882381
OpenAlexW2032372953

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.