Evidence map›Paper›PMID 17881801›Full record

ArticlePhysics in medicine and biology2007

Validation of the flash-evoked response from fetal MEG.

J McCubbin, P Murphy, H Eswaran, H Preissl, T Yee, S E Robinson, J Vrba

Open access · greenAbstract readEvaluation StudyValidation Study
In one paragraph

Article in Physics in medicine and biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Indices and detectors for fetal MCG actography.IEEE transactions on bio-medical engineering · 2011
    Article
  8. Article
  9. Article
  10. Article
  11. Neonatal and fetal response decrement of evoked responses: a MEG study.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

J McCubbinDepartment of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
P Murphy
H Eswaran
H Preissl
T Yee
S E Robinson
J Vrba
University of Arkansas for Medical Sciences · USCoquitlam College · CAHenry Ford Hospital · USUniversity of Toronto · CA

Funding

FETAL MAGNETOENCEPHALOGRAPHY AND EVOKED POTENTIALSR01NS036277 · NINDS · UNIV OF ARKANSAS FOR MED SCIS · PI LOWERY, CURTIS L · 1998 to 2011
$7.0M
Temporal-Spatial Biomagnetic Fields of the FetusR33EB000978 · NIBIB · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI LOWERY, CURTIS L · 2002 to 2004
$1.9M
NIBIB NIH HHS 1R33EB00978-01NIBIB NIH HHS R33 EB000978NINDS NIH HHS 1R01NS367704A1NINDS NIH HHS R01 NS036277
6 · The paper itself

Abstract

Flash-evoked responses can be recorded from the fetus in utero. However, a standard analysis approach based on orthogonal projection (OP) to attenuate maternal and fetal cardiac signals leads to a spatial redistribution of the signal. This effect prevents the correlation of source location with a known fetal head location in some cases and the signal-to-noise ratio (SNR) is sometimes limited such that the response latency is difficult to determine. We used a modified beamformer model search analysis to avoid the redistribution shortcoming and to improve the SNR. We included a statistical test for residual interference in the average and quantified significance of the evoked response with a bootstrap method. Selected source locations compared favorably to fetal head locations estimated from ultrasound exams. The evoked response time course was found to have a significant post-trigger peak with a latency between about 180 and 770 ms in more than 90% of the subject measurements. These results confirm that the combined application of a beamformer model search and bootstrap significance test provides a validation of the flash-evoked response observed in OP processed fetal MEG channels.

Indexed as

AlgorithmsBrainDiagnosis, Computer-AssistedEvoked Potentials, VisualFetal MonitoringHumansMagnetoencephalographyPhotic StimulationReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID17881801
PMCPMC2600492
OpenAlexW2026060111

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.