Evidence map›Paper›PMID 17881551›Full record

ArticleJournal of clinical microbiology2007

Changing molecular epidemiology of methicillin-resistant Staphylococcus aureus in a small geographic area over an eight-year period.

D S Blanc, C Petignat, A Wenger, G Kuhn, Y Vallet, D Fracheboud, S Trachsel, M Reymond, N Troillet, H H Siegrist and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 69 citations in OpenAlex.

  1. Trial
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  4. Review
  5. Article
  6. Atopic dermatitis-derivedFrontiers in cellular and infection microbiology · 2023
    Article
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  9. Review
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  12. Pulse Field Gel Electrophoresis.Methods in molecular biology (Clifton, N.J.) · 2016
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  14. Article
  15. Article
  16. Article
  17. MRSA SCCmec epidemiology in Israel: development and implementation of an MRSA SCCmec typing strategy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2011
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

D S BlancCentre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland. Dominique.Blanc@chuv.ch
C Petignat
A Wenger
G Kuhn
Y Vallet
D Fracheboud
S Trachsel
M Reymond
N Troillet
H H Siegrist
S Oeuvray
M Bes
J Etienne
J Bille
P Francioli
G Zanetti
University Hospital of Lausanne · CHUniversity of Lausanne · CHUniversité Claude Bernard Lyon 1 · FRFribourg Development Agency · CHHôpital du Valais · CHInternational Museum of Horology · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) at an international level shows that most MRSA strains belong to a few pandemic clones. At the local level, a predominance of one or two clones was generally reported. However, the situation is evolving and new clones are emerging worldwide, some of them with specific biological characteristics, such as the presence of Panton-Valentine leucocidin (PVL). Understanding these changes at the local and international levels is of great importance. Our objective was to analyze the evolution of MRSA epidemiology at multiple sites on a local level (Western Switzerland) over a period of 8 years. Data were based on MRSA reports from seven sentinel laboratories and infection control programs covering different areas. Pulsed-field gel electrophoresis was used to type MRSA isolates. From 1997 to 2004, a total of 2,256 patients with MRSA were reported. Results showed the presence of four predominant clones (accounting for 86% of patients), which could be related to known international clones (Berlin, New York/Japan, Southern Germany, and Iberian clones). Within the small geographic region, the 8-year follow-up period in the different areas showed spacio-temporal differences in the relative proportions of the four clones. Other international MRSA clones, as well as clones showing genetic characteristics identical to those of community-acquired MRSA (SCCmec type IV and the presence of PVL genes), were also identified but presumably did not disseminate. Despite the worldwide predominance of a few MRSA clones, our data showed that at a local level, the epidemiology of MRSA might be different from one hospital to another. Moreover, MRSA clones were replaced by other emerging clones, suggesting a rapid change.

Indexed as

Methicillin ResistanceElectrophoresis, Gel, Pulsed-FieldEmigrants and ImmigrantsHumansStaphylococcal InfectionsStaphylococcus aureusTime Factors

Identifiers

PMID17881551
PMCPMC2168490
OpenAlexW2151288713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.