ArticleActa paediatrica (Oslo, Norway : 1992)2007
Lung function and bronchial hyper-responsiveness 11 years after hospitalization for bronchiolitis.
Article in Acta paediatrica (Oslo, Norway : 1992), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Associations of α- and γ-tocopherol during early life with lung function in childhood.The Journal of allergy and clinical immunology · 2020Trial
- Respiratory Syncytial Virus: A Narrative Review of Updates and Recent Advances in Epidemiology, Pathogenesis, Diagnosis, Management and Prevention.Journal of clinical medicine · 2025Review
- Early-life pulmonary viral infection leads to long-term functional and lower airway structural changes in the lungs.American journal of physiology. Lung cellular and molecular physiology · 2024Article
- Bronchial reactivity and asthma at school age after early-life metapneumovirus infection.ERJ open research · 2024Article
- Association between severe bronchiolitis in infancy and age 6-year lung function.Respiratory medicine · 2023Article
- Are Babies Born Preterm High-Risk Asthma Candidates?Journal of clinical medicine · 2023Review
- Asthma, atopy and lung function in young adults after hospitalisation for bronchiolitis in infancy: impact of virus and sex.BMJ open respiratory research · 2022Article
- A Durable Relationship: Respiratory Syncytial Virus Bronchiolitis and Asthma past Their Golden Anniversary.Vaccines · 2020Review
- Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing.Allergy · 2019Article
- The Burden and Long-term Respiratory Morbidity Associated with Respiratory Syncytial Virus Infection in Early Childhood.Infectious diseases and therapy · 2017Review
- Recurrent wheezing 36 months after bronchiolitis is associated with rhinovirus infections and blood eosinophilia.Acta paediatrica (Oslo, Norway : 1992) · 2014Article
- Respiratory syncytial virus--a comprehensive review.Clinical reviews in allergy & immunology · 2013Review
- Article
- Viral infections in children with community-acquired pneumonia.Current infectious disease reports · 2013Article
- Pulmonary function testing in young children.Current allergy and asthma reports · 2011Review
- Early wheeze as reported by mothers and lung function in 4-year-olds. Prospective cohort study in Krakow.Pediatric pulmonology · 2010Article
- The year in review.Paediatric respiratory reviews · 2009Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimAtopic infants hospitalized for wheezing not caused by respiratory syncytial virus (RSV) carry the highest risk for later asthma. In the present paper, early risk factors for later lung function abnormalities and for bronchial hyper-responsiveness (BHR) were evaluated in 81 children, hospitalized for bronchiolitis in infancy, at the median age of 12.3 years.
methodsThe basic data, including data on atopy in children and viral aetiology of bronchiolitis, had been collected on entry to the study at less than 2 years of age. Lung function was studied by flow-volume spirometry (FVS), and BHR by methacholine and exercise challenge tests 11.4 years after hospitalization during infancy.
resultsRSV aetiology of bronchiolitis was associated with reduced forced vital capacity (FVC; 93.65% of predicted +/- 11.05 vs. 99.57%+/- 12.59, p = 0.009). Early sensitization to inhalant allergens (OR 12.59, 95% CI 2.30-68.77) and maternal smoking during pregnancy (OR 4.58, 95% CI 1.28-16.39) were associated with BHR to exercise, and early atopic dermatitis (OR 3.48, 95% CI 1.09-11.10) was associated with BHR to methacholine.
conclusionsRSV bronchiolitis was associated with a restrictive pattern of lung function. Early atopy and maternal smoking during pregnancy may play a role in the development and persistence of BHR.
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