ReviewInternational journal of experimental pathology2007
Central nervous system capillary haemangioblastoma: the pathologist's viewpoint.
Review in International journal of experimental pathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety and efficacy of surgical treatment for brainstem hemangioblastoma: a meta-analysis.Neurosurgical review · 2021Pooled it
- Article
- Pathological features and clinical outcomes of hemangioblastoma in the spinal cord of three dogs.The Journal of veterinary medical science · 2026Article
- Fatal hemangioblastoma: a case report and literature review.Frontiers in oncology · 2026Review
- Hemangioblastoma of the Kidney-A Comprehensive Clinical, Pathological, and Genetic Analysis of Four Cases.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Canine Hemangioblastoma: Case Series and Literature Review.Animals : an open access journal from MDPI · 2025Article
- Radiosurgically Treated Recurrent Cerebellar Hemangioblastoma: A Case Report and Literature Review.Current oncology (Toronto, Ont.) · 2024Review
- Article
- Article
- Article
- A bibliometric analysis of the top 100 cited articles for hemangioblastoma of the central nervous system.Neurosurgical review · 2023Review
- Case report: High-resolution, intra-operative µDoppler-imaging of spinal cord hemangioblastoma.Frontiers in surgery · 2023Article
- Cerebellar Hemangioblastoma with Leptomeningeal Spread and a Fatal Outcome: A Rare Case Report withInternational medical case reports journal · 2023Article
- Benign Spinal Tumors.Advances in experimental medicine and biology · 2023Article
- Rare massive hepatic hemangioblastoma: A case report.World journal of gastrointestinal oncology · 2022Article
- Usefulness of neuroimaging and immunohistochemical study for accurate diagnosis of parasagittal hemangioblastoma arising in the supratentorial region: a case report and review of the literature.Translational cancer research · 2022Article
- Von Hippel-Lindau disease with extramedullary and pancreatic involvement.Medical journal, Armed Forces India · 2022Article
- Advanced magnetic resonance imaging findings of cerebellar hemangioblastomas: A report of three cases and a literature review.Acta radiologica open · 2022Article
- Anlotinib for the Treatment of Multiple Recurrent Lumbar and Sacral Cord Hemangioblastomas: A Case Report.Frontiers in oncology · 2022Article
- Clinical characteristics, surgical management, and prognostic factors for supratentorial hemangioblastoma: A retrospective study.Frontiers in surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haemangioblastomas are rare neoplasms of uncertain histogenesis. They represent 1.5-2.5% of intracranial tumours. While the cerebellum is by far the most frequent site, these lesions also tend to occur in the medulla and spinal cord. Most haemangioblastomas are sporadic but up to one quarter are associated with Von Hippel-Lindau disease (VHL). Although a fairly good number of haemangioblastomas were reported, a lack of side-by-side analysis of these reports has resulted in tentative conclusions that merely offer a first glimpse at their clinicopathologic diversity and histogenesis. To remedy this issue, this study presents a literature review concerning these lesions. Medline literature including both relevant monographs and clinicopathological case series. Haemangioblastomas occur either as a part of VHL disease (25-30%, inherited mutation of VHL gene on 3p25-26 chromosome) or as sporadic tumours (often with somatic mutation of VHL gene). They have diverse clinicopathologic presentations with cerebellar lesions having a better prognosis than their brainstem counterparts. Immunostaining is important for separation of haemangioblastomas from other tumours with similar histology. The rich vascularity of haemangioblastomas is due to overexpression of vascular endothelial growth factors. Moreover, 'stromal' cells represent the neoplastic cells of haemangioblastomas and are capable of forming blood islands with extramedullary haematopoiesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.