ArticleInternational journal of hematology2007
Intensified strategies to control vancomycin-resistant enterococci in immunocompromised patients.
Article in International journal of hematology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A systematic review of the effectiveness of cohorting to reduce transmission of healthcare-associatedInfection control and hospital epidemiology · 2020Pooled it
- Temporal trend and individual and hospital characteristics associated to vancomycin-resistant Enterococcus faecium bloodstream infections: a retrospective analysis from the national surveillance system, Italy 2015-2023.Antimicrobial resistance and infection control · 2025Observational
- Healthcare-associated infections over an eight year period in a large university hospital in Sicily (Italy, 2011-2018).Journal of infection prevention · 2021Article
- Novel Small-molecule Antibacterials against Gram-positive Pathogens ofAntibiotics (Basel, Switzerland) · 2019Article
- Nematode-Associated Bacteria: Production of Antimicrobial Agent as a Presumptive Nominee for Curing Endodontic Infections Caused byFrontiers in microbiology · 2019Article
- Novel Effective Small-Molecule Antibacterials against Enterococcus Strains.Molecules (Basel, Switzerland) · 2017Article
- Outbreaks caused by vancomycin-resistantHeliyon · 2017Article
- Fecal microbial transplantation as a therapeutic option in patients colonized with antibiotic resistant organisms.Gut microbes · 2017Review
- Weekly screening supports terminating nosocomial transmissions of vancomycin-resistant enterococci on an oncologic ward - a retrospective analysis.Antimicrobial resistance and infection control · 2017Article
- Where is the difference between an epidemic and a high endemic level with respect to nosocomial infection control measures? An analysis based on the example of vancomycin-resistant Enterococcus faecium in hematology and oncology departments.GMS hygiene and infection control · 2017Review
- New insights into the antimicrobial effect of mast cells against Enterococcus faecalis.Infection and immunity · 2014Article
- [Requirements for hygiene in the medical care of immunocompromised patients. Recommendations from the Committee for Hospital Hygiene and Infection Prevention at the Robert Koch Institute (RKI)].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2010Article
- Outbreak of vancomycin-resistant enterococcus colonization among pediatric oncology patients.Infection control and hospital epidemiology · 2009Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing colonization and infection with vancomycin-resistant enterococci (VRE) in immunocompromised patients are associated with increased mortality. Despite contact precautions for VRE control, rapid limitation of its spread is often impossible. We report on a VRE outbreak in a hematologic/oncologic unit including 33 patients. Although 28 of the patients had only VRE colonization, VRE-related infection was probable in 4 patients, and VRE infection of the bloodstream occurred in 1 case. Two patients were identified by VRE screening on admission, 20 were identified by weekly routine VRE screening, and 6 were identified from specimens taken to clarify infections (eg, urine, bronchoalveolar lavage). Five individuals acquired VRE colonization as inpatients (contact patients). Multiple-locus variable-number tandem repeat analysis (MLVA) proved that the outbreak was caused by VanA gene-positive Enterococcus faecium belonging to MLVA genogroup C1(MLVA types 1, 7, 12). The outbreak strains exhibited the potential virulence factor esp(enterococcus surface protein). The outbreak was terminated within 2 months by intensified infection-control measures, including quarantine and the cohorting of patients who tested positive for VRE; however, VRE spread recurred after the measures were discontinued but was again limited by resuming the measures. We conclude that intensive infection-control strategies enable the timely termination of VRE outbreaks, even those involving VRE strains with high epidemic potential on "high-risk wards" (eg, hematologic/oncologic units). Premature discontinuation of infection-control measures may cause recurrence of the VRE spread.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.