ReviewCurrent opinion in immunology2007
Evolution and development of immunological structures in the lamprey.
Review in Current opinion in immunology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 101 citations in OpenAlex.
- Variable lymphocyte receptor F is generated via somatic diversification and expressed by lamprey T-like cells.Nature communications · 2025Article
- Evolutionary History of Bilaterian FoxP Genes: Complex Ancestral Functions and Evolutionary Changes Spanning 2R-WGD in the Vertebrate Lineage.Molecular biology and evolution · 2025Article
- Function and Regulation of Bone Marrow Adipose Tissue in Health and Disease: State of the Field and Clinical Considerations.Comprehensive Physiology · 2024Review
- Splenic stromal niches in homeostasis and immunity.Nature reviews. Immunology · 2023Review
- Granulin as an important immune molecule involved in lamprey tissue repair and regeneration by promoting cell proliferation and migration.Cellular & molecular biology letters · 2022Article
- MicroRNA expression profile in Lampetra morii upon Vibrio anguillarum infection and miR-4561 characterization targeting lip.Communications biology · 2021Article
- Article
- Putative Immunological Functions of Inducible Skin-Associated Lymphoid Tissue in the Context of Mucosa-Associated Lymphoid Tissue.Frontiers in immunology · 2021Review
- A novel protein upstream stimulatory factor 2 identified in lamprey, Lethenteron reissneri.Development genes and evolution · 2020Article
- Molecular Characterization and Chemotactic Function of CXCL8 in Northeast Chinese Lamprey (Frontiers in immunology · 2020Article
- Hematopoiesis: A Layered Organization Across Chordate Species.Frontiers in cell and developmental biology · 2020Review
- A novel CDK-2 homolog identified in lamprey, Lampetra japonica, with roles in apoptosis.Fish physiology and biochemistry · 2019Article
- Determination of the Role and Active Sites of PKC-Delta-Like from Lamprey in Innate Immunity.International journal of molecular sciences · 2019Article
- Conservation of sequence motifs suggests that the nonclassical MHC class I lineages CD1/PROCR and UT were established before the emergence of tetrapod species.Immunogenetics · 2018Article
- Label-Free Quantitative Proteomic Reveals Differentially Expressed Proteins in Aeromonas-Immunostimulated Leukocytes of Lampetra japonica.Current microbiology · 2018Article
- Protection from UV light is an evolutionarily conserved feature of the haematopoietic niche.Nature · 2018Article
- Lamprey Prohibitin2 Arrest G2/M Phase Transition of HeLa Cells through Down-regulating Expression and Phosphorylation Level of Cell Cycle Proteins.Scientific reports · 2018Article
- Redefining Memory: Building the Case for Adaptive NK Cells.Journal of virology · 2017Review
- Identification and characterisation of lamprey protein kinase C delta-like gene.Scientific reports · 2017Article
- A Novel Vav3 Homolog Identified in Lamprey, Lampetra japonica, with Roles in Lipopolysaccharide-Mediated Immune Response.International journal of molecular sciences · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Comparative immunology has been revitalized by the integration of genomics approaches, which allow a foothold into addressing problems that previously had been difficult to study. One such problem had been the enigmatic finding of overt immune anatomical structures in the lamprey, yet its apparent lack of bona fide immunoglobulin or T cell receptor molecules. The genomic characterization of a novel extended locus that undergoes rearrangements to generate receptor diversity and the subsequent implementation of this diversity in the immune system of lampreys have generated considerable interest as well as new avenues for investigation. Here, we review the anatomical structures of the lamprey that exhibit lympho-hematopoietic characteristics, with the ultimate goal of reconciling these data with contemporary molecular findings. By integrating these datasets we seek to better understand how an alternative adaptive immune system could have evolved.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.