Evidence map›Paper›PMID 17874281›Full record

ArticleMycopathologia2007

Candida parapsilosis fungemia in neonates: genotyping results suggest healthcare workers hands as source, and review of published studies.

Eveline C van Asbeck, Yhu-Chering Huang, Angela N Markham, Karl V Clemons, David A Stevens

Abstract read
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In one paragraph

Article in Mycopathologia, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Pooled it
  2. Article
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  6. Journal of fungi (Basel, Switzerland) · 2023
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  8. Characteristics of Biofilms Formed byJournal of fungi (Basel, Switzerland) · 2022
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  9. Article
  10. Preterm Infants Harbour a Rapidly Changing Mycobiota That IncludesJournal of fungi (Basel, Switzerland) · 2020
    Article
  11. Article
  12. The Epidemiology and Susceptibility of Candidemia in Jerusalem, Israel.Frontiers in cellular and infection microbiology · 2019
    Article
  13. Article
  14. Candida auris: an Emerging Fungal Pathogen.Journal of clinical microbiology · 2018
    Review
  15. An Azole-ResistantFrontiers in microbiology · 2018
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Eveline C van AsbeckDivision of Infectious Diseases, Santa Clara Valley Medical Center, California Institute for Medical Research, 751 South Bascom Avenue, San Jose, CA 95128, USA.
Yhu-Chering Huang
Angela N Markham
Karl V Clemons
David A Stevens
California Institute for Medical Research · USChang Gung University · TWSanta Clara Valley Medical Center · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An outbreak of Candida parapsilosis fungemia involving 17 neonatal intensive care unit (NICU) patients was studied. There were 14 blood culture and nine colonizing isolates from other sites available. The hands of NICU healthcare workers (HCW) yielded eight isolates. Screening of the isolates by random amplified polymorphic DNA (RAPD) method showed only three profiles. Typing by restriction fragment length polymorphism (RFLP) revealed all blood isolates were RFLP subtype VII-1. Among the nine infant colonizing isolates, there were four different RFLP subtypes; four of the isolates were subtype VII-1. Seven of the eight isolates from HCW were RFLP subtype VII-1. The majority of infant colonizers were not found in the blood, suggesting a possible direct spread of the epidemic subtype VII-1 strain from HCW hands to infant blood. The source of the infant colonizing strains is unclear, but non-VII-1 strains may be largely of maternal origin and VII-1 strains from HCW. These findings reinforce prior studies that have implicated HCW hands as the source of nosocomial, including neonatal, fungemia.

Indexed as

Disease OutbreaksCandidaCandidiasisCluster AnalysisCross InfectionDNA, FungalFungemiaHealth PersonnelHumansInfant, NewbornInfant, Very Low Birth WeightInfectious Disease Transmission, Professional-to-PatientPolymorphism, Restriction Fragment LengthRandom Amplified Polymorphic DNA TechniqueTaiwanDNA, Fungal

Identifiers

PMID17874281
OpenAlexW2022619474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.