Evidence map›Paper›PMID 17874035›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2007

Isolated diastolic dysfunction--diagnostic value of tissue Doppler imaging, colour M-mode and N-terminal pro B-type natriuretic peptide.

S Hettwer, B Panzner-Grote, R Witthaut, K Werdan

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Diastolic function measurements and diagnostic consequences: a comparison of pulsed wave- and color-coded tissue Doppler imaging.Clinical research in cardiology : official journal of the German Cardiac Society · 2010
    Article
  3. Effects of mild hypothermia on hemodynamics in cardiac arrest survivors and isolated failing human myocardium.Clinical research in cardiology : official journal of the German Cardiac Society · 2010
    Article
  4. Article
  5. Natriuretic peptides in the detection of preclinical diastolic or systolic dysfunction.Clinical research in cardiology : official journal of the German Cardiac Society · 2010
    Article
  6. Article
  7. Clinical implications of the echocardiographic assessment of left ventricular long axis function.Clinical research in cardiology : official journal of the German Cardiac Society · 2009
    Review
  8. Clinical variables affecting survival in patients with decompensated diastolic versus systolic heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

S HettwerMartin-Luther-University, Halle-Wittenberg, Department of Medicine III, Ernst-Grube-Str. 40, 06097, Halle/Saale, Germany. stefan.hettwer@medizin.uni-halle.de
B Panzner-Grote
R Witthaut
K Werdan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFor diagnosis of diastolic dysfunction of the left ventricle (DDF), measurement of relaxation velocity (V(R)) by tissue Doppler imaging (V(R)), flow propagation velocity of transmitral inflow (v(p)) as well as the measurement of serum levels of N-terminal pro b-type natriuretic peptide (NT-proBNP) compete with the standard echocardiographic DDF-measures because of several disadvantages of the latter.

methodsWe examined the diagnostic value of method 1, 2 and NT-proBNP in 120 patients with echocardiographic-proven DDF and in 20 patients without. Patients were classified according to the DDF-stage by standard echocardiographic parameters (transmitral E/A-ratio, deceleration time, isovolumetric relaxation time) into stage I, II and III and furthermore subdivided by the presence of dyspnoea.

resultsV(R) and v(p) were significantly lower in patients with DDF than in patients without DDF, with no difference between the various DDF stages. Symptomatic patients showed a trend to a lower V(R). NT-proBNP was elevated in patients with DDF: Symptomatic patients with a DDF at stage I and patients with a DDF at stage II and III independent of the presence of symptoms had elevated NT-proBNP levels.

conclusionAll three methods tested identified patients with DDF. NT-proBNP and v(p) were able to discriminate between symptomatic and asymptomatic patients.

Indexed as

DiastoleEchocardiography, DopplerAgedArea Under CurveBlood Flow VelocityEchocardiography, Doppler, ColorFemaleHumansMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsROC CurveVentricular Dysfunction, LeftNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.