Evidence map›Paper›PMID 17873407›Full record

ReviewMolecular biotechnology2007

Microarray analysis: basic strategies for successful experiments.

Scott A Ness

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Conventional and molecular diagnostic testing for the acute neurologic patient.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2010
    Review
  3. Application of "omics" to prion biomarker discovery.Journal of biomedicine & biotechnology · 2010
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Scott A NessDepartment of Molecular Genetics & Microbiology, Keck-UNM Genomics Resource and UNM Cancer Research and Treatment Center, University of New Mexico HSC, Albuquerque, NM 87131-0001, USA. ness@unm.edu

Funding

TRANSFORMING FUNCTIONS OF THE V-MYB ONCOGENE PRODUCTR01CA058443 · NCI · UNIVERSITY OF NEW MEXICO · PI NESS, SCOTT A. · 1995 to 2010
$2.6M
Myb protein specificity in human hematopoietic cellsR01CA105257 · NCI · UNIVERSITY OF NEW MEXICO · PI NESS, SCOTT A. · 2005 to 2009
$1.3M
NCI NIH HHS R01 CA058443NCI NIH HHS R01 CA105257
6 · The paper itself

Abstract

Microarrays offer a powerful approach to the analysis of gene expression that can be used for a wide variety of experimental purposes. However, there are several types of microarray platforms that are available. In addition, microarray experiments are expensive and generate complicated data sets that can be difficult to interpret. Success with microarray approaches requires a sound experimental design and a coordinated and appropriate use of statistical tools. Here, the advantages and pitfalls of utilizing microarrays are discussed, as are practical strategies to help novice users succeed with this method that can empower them with the ability to assay changes in gene expression at the whole genome level.

Indexed as

AnimalsGene Expression ProfilingHumansMiceOligonucleotide Array Sequence AnalysisRatsResearch Design

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.