Evidence map›Paper›PMID 17873344›Full record

ReviewStem cell reviews2007

The emerging picture of the mouse mammary stem cell.

François Vaillant, Marie-Liesse Asselin-Labat, Mark Shackleton, Geoffrey J Lindeman, Jane E Visvader

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  12. p53 in stem cells.World journal of biological chemistry · 2011
    Article
  13. Breast cancer stem cell hypothesis: clinical relevance (answering breast cancer clinical features).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2010
    Review
  14. Article
  15. Article
  16. Review
  17. Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2008
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

François VaillantVictorian Breast Cancer Research Consortium Laboratory, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3050, Australia.
Marie-Liesse Asselin-Labat
Mark Shackleton
Geoffrey J Lindeman
Jane E Visvader
Walter and Eliza Hall Institute of Medical Research · AUUniversity of Michigan–Ann Arbor · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The isolation and characterisation of mammary stem cells is an important step towards elucidating the hierarchy of epithelial cell development in the mammary gland and identifying cells that are targets of breast carcinogenesis. Mammary stem cells have recently been prospectively isolated through the identification of specific cell surface markers and in vivo transplantation into cleared fat pads. These cells were demonstrated to reconstitute an entire mammary gland comprising all mature epithelial cell types and to be capable of self-renewal on serial transplantation, thus possessing the defining features of stem cells. Notably, mouse mammary stem cells were found to share the hallmark properties of the basal subtype of breast cancer. This review will summarize the strategy used in the identification of mouse mammary stem cells and their characterisation.

Indexed as

AnimalsAntigens, DifferentiationBreast NeoplasmsCell DifferentiationCell SeparationEpithelial CellsFemaleHumansMammary Glands, AnimalMammary Glands, HumanMammary Neoplasms, AnimalMiceStem CellsStem Cell TransplantationAntigens, Differentiation

Identifiers

PMID17873344
OpenAlexW2074932544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.