ArticleThe Plant cell2007
The Arabidopsis CLASP gene encodes a microtubule-associated protein involved in cell expansion and division.
Article in The Plant cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
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Who cites it
115 citing papers in PubMed, 225 citations in OpenAlex.
- Cellular dynamics and molecular signaling networks of plant cytokinesis.Molecules and cells · 2026Review
- Effect of phosphorus deficiency on biomass and root system architecture in diverseFrontiers in plant science · 2026Article
- Inhibition of Sterol Biosynthesis Alters Tubulin Association with Detergent-Insoluble Membranes and Affects Microtubule Organization in Pollen Tubes ofPlants (Basel, Switzerland) · 2025Article
- Genetic and histological characterization of a dwarf mutant in melon (Cucumis melo L.) reveals potential for breeding semi-dwarf cultivars.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- A Genome-Wide Association Screen for Genes Affecting Leaf Trichome Development and Epidermal Metal Accumulation in Arabidopsis.Plant, cell & environment · 2025Article
- Association mapping and identification of candidate genes for callus induction and regeneration using sorghum mature seeds.Frontiers in plant science · 2025Article
- CLASP-mediated competitive binding in protein condensates directs microtubule growth.Nature communications · 2024Article
- A divergent tumor overexpressed gene domain and oligomerization contribute to SPIRAL2 function in stabilizing microtubule minus ends.The Plant cell · 2024Article
- Identification of bZIP Transcription Factors That Regulate the Development of Leaf Epidermal Cells inInternational journal of molecular sciences · 2024Article
- Morphological Analyses and QTL Mapping of Mottled Leaf in Zucchini (International journal of molecular sciences · 2024Article
- Article
- SPINDLY O-fucosylates nuclear and cytoplasmic proteins involved in diverse cellular processes in plants.Plant physiology · 2023Article
- Brassinosteroid signals cooperate with katanin-mediated microtubule severing to control stamen filament elongation.The EMBO journal · 2023Article
- Genome-wide association analysis for drought tolerance and associated traits in faba bean (Frontiers in plant science · 2023Article
- New insights into light spectral quality inhibits the plasticity elongation of maize mesocotyl and coleoptile during seed germination.Frontiers in plant science · 2023Article
- Construction of prediction models for growth traits of soybean cultivars based on phenotyping in diverse genotype and environment combinations.DNA research : an international journal for rapid publication of reports on genes and genomes · 2022Article
- CLASP balances two competing cell division plane cues during leaf development.Nature plants · 2022Article
- Cell biology of primary cell wall synthesis in plants.The Plant cell · 2022Review
- Genetic Insight Into the Insect Resistance in Bread Wheat Exploiting the Untapped Natural Diversity.Frontiers in genetics · 2022Article
- Rice microtubule-associated protein OsMAP65-3.1, but not OsMAP65-3.2, plays a critical role in phragmoplast microtubule organization in cytokinesis.Frontiers in plant science · 2022Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Controlling microtubule dynamics and spatial organization is a fundamental requirement of eukaryotic cell function. Members of the ORBIT/MAST/CLASP family of microtubule-associated proteins associate with the plus ends of microtubules, where they promote the addition of tubulin subunits into attached kinetochore fibers during mitosis and stabilize microtubules in the vicinity of the plasma membrane during interphase. To date, nothing is known about their function in plants. Here, we show that the Arabidopsis thaliana CLASP protein is a microtubule-associated protein that is involved in both cell division and cell expansion. Green fluorescent protein-CLASP localizes along the full length of microtubules and shows enrichment at growing plus ends. Our analysis suggests that CLASP promotes microtubule stability. clasp-1 T-DNA insertion mutants are hypersensitive to microtubule-destabilizing drugs and exhibit more sparsely populated, yet well ordered, root cortical microtubule arrays. Overexpression of CLASP promotes microtubule bundles that are resistant to depolymerization with oryzalin. Furthermore, clasp-1 mutants have aberrant microtubule preprophase bands, mitotic spindles, and phragmoplasts, indicating a role for At CLASP in stabilizing mitotic arrays. clasp-1 plants are dwarf, have significantly reduced cell numbers in the root division zone, and have defects in directional cell expansion. We discuss possible mechanisms of CLASP function in higher plants.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.